Frontiers in Immunology | Primary Immunodeficiencies

Case Report

Published on 13 Apr 2022

Case Report: A Novel CXCR4 Mutation in a Chinese Child With Kawasaki Disease Causing WHIM Syndrome

in Primary Immunodeficiencies

Xiaopeng Ma
Yaping Wang
Peng Wu
Meiyun Kang
Yue Hong
Yao Xue
Chuqin Chen
Huimin Li
Yongjun Fang

Frontiers in Immunology

doi 10.3389/fimmu.2022.857527

4,240 views
5 citations

Case Report

Published on 11 Apr 2022

Case Report: A Highly Variable Clinical and Immunological Presentation of IKAROS Deficiency in a Single Family

in Primary Immunodeficiencies

Taco W. Kuijpers
Samantha A. M. Tromp
Ester M. M. van Leeuwen
Godelieve J. de Bree

Frontiers in Immunology

doi 10.3389/fimmu.2022.865838

3,866 views
8 citations

Perspective

Published on 11 Apr 2022

Molecular Diagnosis Is Vital to the Accurate Classification and Management of Thrombotic Thrombocytopenic Purpura in Children

in Primary Immunodeficiencies

Cecile L. Karsenty
Susan E. Kirk
Hannah L. Helber
Jose M. Esquilin
Jenny M. Despotovic
Amanda B. Grimes

Frontiers in Immunology

doi 10.3389/fimmu.2022.836960

5,380 views
5 citations

Case Report

Published on 11 Apr 2022

Case Report: Atypical Manifestations Associated With FOXP3 Mutations. The “Fil Rouge” of Treg Between IPEX Features and Other Clinical Entities?

in Primary Immunodeficiencies

Micaela Gentile
Maurizio Miano
Paola Terranova
Stefano Giardino
Maura Faraci
Filomena Pierri
Enrico Drago
Daniela Verzola
Gianmarco Ghiggeri
Enrico Verrina

Frontiers in Immunology

doi 10.3389/fimmu.2022.854749

5,858 views
11 citations

Case Report

Published on 08 Apr 2022

Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency

in Primary Immunodeficiencies

Moisés Labrador-Horrillo
Clara Franco-Jarava
Marina Garcia-Prat
Alba Parra-Martínez
María Antolín
Sandra Salgado-Perandrés
Aina Aguiló-Cucurull
Mónica Martinez-Gallo
Roger Colobran

Frontiers in Immunology

doi 10.3389/fimmu.2022.881206

8,385 views
13 citations

Review

Published on 07 Apr 2022

The Role of Cytokines and Chemokines in Severe Acute Respiratory Syndrome Coronavirus 2 Infections

in Primary Immunodeficiencies

Ren-Jun Hsu
Wei-Chieh Yu
Guan-Ru Peng
Chih-Hung Ye
SuiYun Hu
Patrick Chun Theng Chong
Kah Yi Yap
Jamie Yu Chieh Lee
Wei-Chen Lin
Shu-Han Yu

Frontiers in Immunology

doi 10.3389/fimmu.2022.832394

20,742 views
126 citations

Review

Published on 06 Apr 2022

Pathogenesis of Autoimmune Cytopenias in Inborn Errors of Immunity Revealing Novel Therapeutic Targets

in Primary Immunodeficiencies

Manuela Cortesi
Annarosa Soresina
Laura Dotta
Chiara Gorio
Marco Cattalini
Vassilios Lougaris
Fulvio Porta
Raffaele Badolato

Frontiers in Immunology

doi 10.3389/fimmu.2022.846660

10,683 views
15 citations

Original Research

Published on 06 Apr 2022

Immune Dysregulation in Monogenic Inborn Errors of Immunity in Oman: Over A Decade of Experience From a Single Tertiary Center

in Primary Immunodeficiencies

Tariq Al Farsi
Khwater Ahmed
Jalila Alshekaili
Mahmood Al Kindi
Matthew Cook
Aliya Al-Hosni
Zainab Ansari
Iman Nasr
Nashat Al Sukaiti

Frontiers in Immunology

doi 10.3389/fimmu.2022.849694

4,798 views
6 citations

Case Report

Published on 05 Apr 2022

Case Report: “Primary Immunodeficiency”—Severe Autoimmune Enteropathy in a Pediatric Heart Transplant Recipient Treated With Abatacept and Alemtuzumab

in Primary Immunodeficiencies

Elizaveta Kalaidina
Elizabeth C. Utterson
Deepa Mokshagundam
Mai He
Shalini Shenoy
Megan A. Cooper

Frontiers in Immunology

doi 10.3389/fimmu.2022.863218

3,685 views
4 citations

Review

Published on 04 Apr 2022

AIOLOS Variants Causing Immunodeficiency in Human and Mice

in Primary Immunodeficiencies

Motoi Yamashita
Tomohiro Morio

Frontiers in Immunology

doi 10.3389/fimmu.2022.866582

6,652 views
11 citations

Systematic Review

Published on 30 Mar 2022

Outcomes of Systemic Treatment in Children and Adults With Netherton Syndrome: A Systematic Review

in Primary Immunodeficiencies

Anouk E. M. Nouwen
Renske Schappin
N. Tan Nguyen
Aviël Ragamin
Anette Bygum
Christine Bodemer
Virgil A. S. H. Dalm
Suzanne G. M. A. Pasmans

Frontiers in Immunology

doi 10.3389/fimmu.2022.864449

11,485 views
24 citations

Original Research

Published on 28 Mar 2022

Diagnosis and Treatment of a Patient With Severe Combined Immunodeficiency Due to a Novel Homozygous Mutation in the IL-7Rα Chain

in Primary Immunodeficiencies

Rana Mansour
Yasmin El Bsat
Anthony Fadel
Youmna El-Orfali
Dolly Noun
Nidale Tarek
Nabil Kabbara
Miguel Abboud
Michel J. Massaad

Frontiers in Immunology

doi 10.3389/fimmu.2022.867837

4,392 views
7 citations

Original Research

Published on 28 Mar 2022

Janus Kinase Inhibitors in the Treatment of Type I Interferonopathies: A Case Series From a Single Center in China

in Primary Immunodeficiencies

Wendao Li
Wei Wang
Wei Wang
Linqing Zhong
Lijuan Gou
Changyan Wang
Jingran Ma
Meiying Quan
Shan Jian
Xiaoyan Tang

Frontiers in Immunology

doi 10.3389/fimmu.2022.825367

10,342 views
45 citations

Opinion

Published on 18 Mar 2022

Primary Immunodeficiencies and Hematologic Malignancies: A Diagnostic Approach

in Primary Immunodeficiencies

Sharat Chandra
Tatiana Kalashnikova
Nicola A. M. Wright
Blachy J. Dávila Saldaña

Frontiers in Immunology

doi 10.3389/fimmu.2022.852937

8,943 views
12 citations

Review

Published on 16 Mar 2022

The Actin Regulators Involved in the Function and Related Diseases of Lymphocytes

in Primary Immunodeficiencies

Jianxuan Sun
Xingyu Zhong
Xiaoyu Fu
Heather Miller
Pamela Lee
Bing Yu
Chaohong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2022.799309

9,773 views
15 citations

Mini Review

Published on 11 Mar 2022

Seeking Relevant Biomarkers in Common Variable Immunodeficiency

in Primary Immunodeficiencies

Hsi-en Ho
Charlotte Cunningham-Rundles

Frontiers in Immunology

doi 10.3389/fimmu.2022.857050

9,079 views
29 citations

Original Research

Published on 10 Mar 2022

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity

in Primary Immunodeficiencies

Sophie Steiner
Tatjana Schwarz
Victor M. Corman
Laura Gebert
Malte C. Kleinschmidt
Alexandra Wald
Sven Gläser
Jan M. Kruse
Daniel Zickler
Alexander Peric

Frontiers in Immunology

doi 10.3389/fimmu.2022.840126

8,382 views
27 citations

Original Research

Published on 10 Mar 2022

Impact of Hypogammaglobulinemia on the Course of COVID-19 in a Non-Intensive Care Setting: A Single-Center Retrospective Cohort Study

in Primary Immunodeficiencies

Riccardo Scarpa
Alessandro Dell’Edera
Carla Felice
Roberta Buso
Francesco Muscianisi
Renato Finco Gambier
Sara Toffolo
Ugo Grossi
Mario Giobbia
Giuseppina Barberio

Frontiers in Immunology

doi 10.3389/fimmu.2022.842643

7,363 views
13 citations

Systematic Review

Published on 09 Mar 2022

Functional and Immune Modulatory Characteristics of Bone Marrow Mesenchymal Stromal Cells in Patients With Aplastic Anemia: A Systematic Review

in Primary Immunodeficiencies

Khaled Atmar
Adam J. Tulling
Arjan C. Lankester
Marije Bartels
Frans J. Smiers
Mirjam van der Burg
Alexander B. Mohseny

Frontiers in Immunology

doi 10.3389/fimmu.2022.859668

5,893 views
10 citations

Original Research

Published on 28 Feb 2022

Risk Factors for Severe COVID-19 and Hospital Admission in Patients With Inborn Errors of Immunity - Results From a Multicenter Nationwide Study

in Primary Immunodeficiencies

Tomas Milota
Marta Sobotkova
Jitka Smetanova
Marketa Bloomfield
Jana Vydlakova
Zita Chovancova
Jiri Litzman
Roman Hakl
Jiri Novak
Ivana Malkusova

Frontiers in Immunology

doi 10.3389/fimmu.2022.835770

6,285 views
32 citations

Case Report

Published on 23 Feb 2022

Case Report: Rotavirus Vaccination and Severe Combined Immunodeficiency in Japan

in Primary Immunodeficiencies

Kay Tanita
Yoshiki Kawamura
Hiroki Miura
Noriko Mitsuiki
Takahiro Tomoda
Kento Inoue
Akihiro Iguchi
Masafumi Yamada
Taro Yoshida
Hideki Muramatsu

Frontiers in Immunology

doi 10.3389/fimmu.2022.786375

6,412 views
6 citations

Original Research

Published on 23 Feb 2022

Integrating Clinics, Laboratory, and Imaging for the Diagnosis of Common Variable Immunodeficiency-Related Granulomatous–Lymphocytic Interstitial Lung Disease

in Primary Immunodeficiencies

Marta Dafne Cabanero-Navalon
Victor Garcia-Bustos
Leonardo Fabio Forero-Naranjo
Eduardo José Baettig-Arriagada
María Núñez-Beltrán
Antonio José Cañada-Martínez
Maria José Forner Giner
Nelly Catalán-Cáceres
Manuela Martínez Francés
Pedro Moral Moral

Frontiers in Immunology

doi 10.3389/fimmu.2022.813491

5,259 views
20 citations

Original Research

Published on 22 Feb 2022

Inborn Errors of Immunity Associated With Type 2 Inflammation in the USIDNET Registry

in Primary Immunodeficiencies

Kelsey L. Smith
Darlene Dai
Bhavi P. Modi
Rahnuma Sara
Elizabeth Garabedian
Rebecca A. Marsh
Jennifer Puck
Elizabeth Secord
Kathleen E. Sullivan
Stuart E. Turvey

Frontiers in Immunology

doi 10.3389/fimmu.2022.831279

5,123 views
16 citations

Original Research

Published on 21 Feb 2022

Pediatric Prediction Model for Low Immunoglobulin G Level Based on Serum Globulin and Illness Status

in Primary Immunodeficiencies

Narissara Suratannon
Phimphika Tantithummawong
Cameron Paul Hurst
Yuda Chongpison
Jongkonnee Wongpiyabovorn
P. Martin van Hagen
Willem A. Dik
Pantipa Chatchatee

Frontiers in Immunology

doi 10.3389/fimmu.2022.825867

6,235 views
5 citations

1,017 articles

articles

Case Report: A Novel CXCR4 Mutation in a Chinese Child With Kawasaki Disease Causing WHIM Syndrome

Case Report: A Highly Variable Clinical and Immunological Presentation of IKAROS Deficiency in a Single Family

Molecular Diagnosis Is Vital to the Accurate Classification and Management of Thrombotic Thrombocytopenic Purpura in Children

Case Report: Atypical Manifestations Associated With FOXP3 Mutations. The “Fil Rouge” of Treg Between IPEX Features and Other Clinical Entities?

Case Report: X-Linked SASH3 Deficiency Presenting as a Common Variable Immunodeficiency

The Role of Cytokines and Chemokines in Severe Acute Respiratory Syndrome Coronavirus 2 Infections

Pathogenesis of Autoimmune Cytopenias in Inborn Errors of Immunity Revealing Novel Therapeutic Targets

Immune Dysregulation in Monogenic Inborn Errors of Immunity in Oman: Over A Decade of Experience From a Single Tertiary Center

Case Report: “Primary Immunodeficiency”—Severe Autoimmune Enteropathy in a Pediatric Heart Transplant Recipient Treated With Abatacept and Alemtuzumab

AIOLOS Variants Causing Immunodeficiency in Human and Mice

Outcomes of Systemic Treatment in Children and Adults With Netherton Syndrome: A Systematic Review

Diagnosis and Treatment of a Patient With Severe Combined Immunodeficiency Due to a Novel Homozygous Mutation in the IL-7Rα Chain

Janus Kinase Inhibitors in the Treatment of Type I Interferonopathies: A Case Series From a Single Center in China

Primary Immunodeficiencies and Hematologic Malignancies: A Diagnostic Approach

The Actin Regulators Involved in the Function and Related Diseases of Lymphocytes

Seeking Relevant Biomarkers in Common Variable Immunodeficiency

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity

Impact of Hypogammaglobulinemia on the Course of COVID-19 in a Non-Intensive Care Setting: A Single-Center Retrospective Cohort Study

Functional and Immune Modulatory Characteristics of Bone Marrow Mesenchymal Stromal Cells in Patients With Aplastic Anemia: A Systematic Review

Risk Factors for Severe COVID-19 and Hospital Admission in Patients With Inborn Errors of Immunity - Results From a Multicenter Nationwide Study

Case Report: Rotavirus Vaccination and Severe Combined Immunodeficiency in Japan

Integrating Clinics, Laboratory, and Imaging for the Diagnosis of Common Variable Immunodeficiency-Related Granulomatous–Lymphocytic Interstitial Lung Disease

Inborn Errors of Immunity Associated With Type 2 Inflammation in the USIDNET Registry

Pediatric Prediction Model for Low Immunoglobulin G Level Based on Serum Globulin and Illness Status