Frontiers in Immunology | Systems Immunology

Correction

Published on 14 Aug 2026

Correction: The gut-liver-immune axis: structural basis, cellular architecture, molecular mediators, and disease-specific manifestations

in Systems Immunology

Sang Jun Yoon
Jung A Eom
Ki Tae Suk

Frontiers in Immunology

doi 10.3389/fimmu.2026.1960070

233 views

Systematic Review

Published on 12 Aug 2026

Immune-inflammatory biomarkers and immune features in metabolic dysfunction-associated steatotic liver disease: a bibliometric study

in Systems Immunology

Zelin Ye
Mingrui Liu
Qingjuan Wu
Jiuchong Wang
Wenliang Lyu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1896838

390 views

Correction

Published on 12 Aug 2026

Correction: IDEIS: a tool to identify PTPRC/CD45 isoforms from single-cell transcriptomic data

in Systems Immunology

Juraj Michalik
Veronika Niederlova
Ondrej Stepanek

Frontiers in Immunology

doi 10.3389/fimmu.2026.1952440

232 views

Original Research

Published on 11 Aug 2026

Prediction of severe sepsis-associated acute kidney injury incorporating immune-inflammatory profiles: development and validation of a machine learning model in a multicenter prospective cohort study

in Systems Immunology

Xiaoxia Guo
Fei Li
Chang Xu
Wenliang Ma
Huimiao Jia
Wenxiong Li
Na Cui

Frontiers in Immunology

doi 10.3389/fimmu.2026.1882789

588 views

Original Research

Published on 11 Aug 2026

Integrated machine learning and transcriptomics reveal immune infiltration-related orthologous transcription genes in cerebral ischemic injury

in Systems Immunology

Hui Xu
Xu Huang
Ming-yang Hong
Jian Xu
Tao-tao Yang
Rui-rui Shi
Jin-hua Gu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1700109

352 views

Review

Published on 11 Aug 2026

Calcimimetics and CaSR signaling in CKD-MBD: bone–immune–vascular crosstalk and therapeutic potential

in Systems Immunology

Cai-Mei Zheng
Hsuan-Chu Hsu
Yi-Chou Hou
Chien-Lin Lu
Jing-Quan Zheng
Kuo-Cheng Lu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1912252

208 views

Review

Published on 11 Aug 2026

Lactate and lactylation in sepsis: regulation of immune-metabolic crosstalk and organ injury

in Systems Immunology

Zhiwang Li
Wan-Jie Gu
Tao Li
Xingui Dai
Xiang-Jie Duan
Feng Yang
Hai-Yan Yin
Zhiming Zhang
Peiyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1900179

590 views

Mini Review

Published on 10 Aug 2026

Glucolipid metabolic dysfunction in ankylosing spondylitis: inflammatory mechanisms, immune–metabolic crosstalk and therapeutic implications of natural products and traditional Chinese medicine

in Systems Immunology

Xiaofei Dong
Jingjing Zhang
Zixuan Chen
Yeqi Liang
Yi Chen
Zheng Xiao
Yingcun Li
Ke Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1874215

708 views

Hypothesis and Theory

Published on 07 Aug 2026

A systemic epithelial–immune–neural framework for pediatric atopic dermatitis–allergic rhinitis comorbidity

in Systems Immunology

Suning Mu
Yijie Wang
Wen Qin
Mengying Mao
Yan Wang
Yuqian Zhang
Youpeng Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1864351

661 views

Clinical Trial

Published on 07 Aug 2026

Transcriptomic and proteomic signatures following AS03-adjuvanted Influenza A/H7N9 vaccine

in Systems Immunology

C. Buddy Creech
Kristen J. Steenbergen
Casey E. Gelber
Leigh M. Howard
Kevin L. Schey
Kristie Lindsey Rose
Sandra M. Yoder
Kathryn M. Edwards
Johannes B. Goll

Frontiers in Immunology

doi 10.3389/fimmu.2026.1786231

829 views

Original Research

Published on 07 Aug 2026

SHAP-interpretable machine learning integrating exposures and multi-omics reveals immune alterations and biomarkers in COPD–lung cancer comorbidity

in Systems Immunology

Yiran Fei
Yinying Chai
Shiyuan Tong
Bohao Sun
Ziqiang Chen
Shiliang Chen
Zhezhong Zhang
Yibo He
Shengliang Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1875146

503 views

Review

Published on 06 Aug 2026

Psoriasis as a spatial immune ecosystem: insights from single-cell and spatial transcriptomics

in Systems Immunology

Wenkang Cheng
Ting Luo
Xiaoyu Zhou
Haixia Jing

Frontiers in Immunology

doi 10.3389/fimmu.2026.1915876

811 views

Mini Review

Accepted on 05 Aug 2026

Circulating Cytokines as Potential Dynamic Biomarkers of PD-1 Blockade Response and Prognosis in Non-Small Cell Lung Cancer

in Systems Immunology

Bo Peng
Yongyuan Li
Shuyuan Li
Jiajun Pan
Weimin Qian
Qingpeng Li

Frontiers in Immunology

284 views

Original Research

Accepted on 05 Aug 2026

Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells

in Systems Immunology

Yue-Ming Gao
Qi Li
Yue Wang
Zhenling Deng

Frontiers in Immunology

199 views

Original Research

Accepted on 05 Aug 2026

A Multicohort Proteomics-Based Machine Learning Score (MASHPredict) for Noninvasive Diagnosis and Long-Term Prognostication of Metabolic Dysfunction-associated Steatohepatitis

in Systems Immunology

Xu Hu
Fanlai Meng
Wei Zhou
Shun Li
Yujie Gao
Yali Zhang
Jie Zhang
Lianhua Kong
Guokun Liu
Xiaohong Shi

Frontiers in Immunology

139 views

Review

Accepted on 05 Aug 2026

Imaging The Fate of CAR-T Cells In Vivo

in Systems Immunology

Hongyi Wang
Yan Yan
Yueping Li
Sihan Chen
Rui Lin
Jinfeng Zhu
Xiaju Cheng

Frontiers in Immunology

265 views

Review

Accepted on 05 Aug 2026

Macrophage Plasticity and Metabolic Control in Muscle Repair and Disease

in Systems Immunology

Jyoti K Jaiswal
James S Novak
Sarah Tiufekchiev-Grieco

Frontiers in Immunology

144 views

Review

Accepted on 05 Aug 2026

The Eight Pillars of Within-host Tuberculosis Modelling

in Systems Immunology

Roselyn Kaondera-Shava
Christian Michael
Denise Kirschner
Ruth Bowness

Frontiers in Immunology

111 views

Original Research

Accepted on 05 Aug 2026

Integrative multi-omics analysis prioritizes compartment-specific candidate targets of gut microbiota metabolites in diabetic kidney disease

in Systems Immunology

Fengwei Xie
Fengwei Xie
Wenjie Chen
Jiahao Li
Sihan Lin
Qihang Bao
Weiqing Li
Junpeng Cheng
Yuan Ma
Ziyu Wu

Frontiers in Immunology

109 views

Original Research

Published on 05 Aug 2026

Germline based SARS-CoV-2 specific B cell repertoire motif identified with novel sequence based bioinformatic pipeline

in Systems Immunology

Daniel Fridman
Lena Israitel
Areen Shtewe
Uri Hershberg

Frontiers in Immunology

doi 10.3389/fimmu.2026.1823750

590 views

Original Research

Published on 05 Aug 2026

Modeling antibody recognition across SARS-CoV-2 and SARS-CoV-1 using epitope-informed transfer learning

in Systems Immunology

Jimmy B. Yuan
Ryan C. Bruneau
Stephen Won
Aidan Elliot Heller
Thomas Sheffield
Kenneth L. Sale
Brooke Harmon
Le Thanh Mai Pham

Frontiers in Immunology

doi 10.3389/fimmu.2026.1886934

578 views

Original Research

Published on 04 Aug 2026

Single-cell RNA sequencing reveals hypoxia-associated stress response signatures in the immune and stromal microenvironment of laryngeal squamous cell carcinoma

in Systems Immunology

Huihui Du
Yating Wang
Renyu Lin
Jiaqi Yu
Kuaiquan Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1850654

604 views

Original Research

Published on 04 Aug 2026

Shared genetic architecture between Crohn’s disease and IgA nephropathy: implications for a gut–immune–kidney axis

in Systems Immunology

Tao Su
Mengjun Liang
Xiaohang Gao
Rui Lin
Hongzhen Wu
Luying Wu
Min Zhang
Tao Liu
Xiang Peng
Junzhang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1905767

594 views

Original Research

Published on 04 Aug 2026

Influence of immune checkpoint inhibitor target and timing on combination treatment with antibody-based β-emitting targeted radionuclide therapy across tumor immunogenicity profiles

in Systems Immunology

Simone C. Kleinendorst
Egbert Oosterwijk
Mark Konijnenberg
Milou Boswinkel
Manon Gloudemans
Sylvia T.M. Wenker
Stijn Muselaers
Peter Mulders
Lyndsey Maffa
Michael F. O’Hara

Frontiers in Immunology

doi 10.3389/fimmu.2026.1872928

948 views

694 articles

articles

Correction: The gut-liver-immune axis: structural basis, cellular architecture, molecular mediators, and disease-specific manifestations

Immune-inflammatory biomarkers and immune features in metabolic dysfunction-associated steatotic liver disease: a bibliometric study

Correction: IDEIS: a tool to identify PTPRC/CD45 isoforms from single-cell transcriptomic data

Prediction of severe sepsis-associated acute kidney injury incorporating immune-inflammatory profiles: development and validation of a machine learning model in a multicenter prospective cohort study

Integrated machine learning and transcriptomics reveal immune infiltration-related orthologous transcription genes in cerebral ischemic injury

Calcimimetics and CaSR signaling in CKD-MBD: bone–immune–vascular crosstalk and therapeutic potential

Lactate and lactylation in sepsis: regulation of immune-metabolic crosstalk and organ injury

Glucolipid metabolic dysfunction in ankylosing spondylitis: inflammatory mechanisms, immune–metabolic crosstalk and therapeutic implications of natural products and traditional Chinese medicine

A systemic epithelial–immune–neural framework for pediatric atopic dermatitis–allergic rhinitis comorbidity

Transcriptomic and proteomic signatures following AS03-adjuvanted Influenza A/H7N9 vaccine

SHAP-interpretable machine learning integrating exposures and multi-omics reveals immune alterations and biomarkers in COPD–lung cancer comorbidity

Psoriasis as a spatial immune ecosystem: insights from single-cell and spatial transcriptomics

Circulating Cytokines as Potential Dynamic Biomarkers of PD-1 Blockade Response and Prognosis in Non-Small Cell Lung Cancer

Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells

A Multicohort Proteomics-Based Machine Learning Score (MASHPredict) for Noninvasive Diagnosis and Long-Term Prognostication of Metabolic Dysfunction-associated Steatohepatitis

Imaging The Fate of CAR-T Cells In Vivo

Macrophage Plasticity and Metabolic Control in Muscle Repair and Disease

The Eight Pillars of Within-host Tuberculosis Modelling

Integrative multi-omics analysis prioritizes compartment-specific candidate targets of gut microbiota metabolites in diabetic kidney disease

Germline based SARS-CoV-2 specific B cell repertoire motif identified with novel sequence based bioinformatic pipeline

Modeling antibody recognition across SARS-CoV-2 and SARS-CoV-1 using epitope-informed transfer learning

Single-cell RNA sequencing reveals hypoxia-associated stress response signatures in the immune and stromal microenvironment of laryngeal squamous cell carcinoma

Shared genetic architecture between Crohn’s disease and IgA nephropathy: implications for a gut–immune–kidney axis

Influence of immune checkpoint inhibitor target and timing on combination treatment with antibody-based β-emitting targeted radionuclide therapy across tumor immunogenicity profiles