Frontiers in Immunology | T Cell Biology

Original Research

Published on 24 Oct 2025

Assessment of antigen-specific T cell recall responses in non-human primates using a composite AIM assay

in T Cell Biology

Jan M. Schmidt
Mayuri Prasad
Kenna Degner
Rebecca Schiavo
Allison Repic
Lauren Little
Laura Israel
Feng Chen
Regine Hansen
Anette C. Karle

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661480

427 views

Original Research

Published on 23 Oct 2025

Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection

in T Cell Biology

Liling Zeng
Li Liu
Baolin Ren
Bing Feng
Xudong Lai
Xunxi Lai
Zhimin Chen
Yihui Huang
Wenxin Hong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680089

2,290 views

Original Research

Accepted on 21 Oct 2025

Defined Metabolic States Shape T Cell Fate and Function Across Culture Conditions

in T Cell Biology

Kayla Sylvester
Natasha Karassina
Anthony C. Lauer
Gediminas Vidugiris
Jolanta Vidugiriene

Frontiers in Immunology

Original Research

Accepted on 20 Oct 2025

Disruption of Notch Signaling by KGF Induces a Developmental Pause in Thymocytes

in T Cell Biology

Ruifeng Teng
Francis A. Flomerfelt
Ping Xue
Constance Tom Noguchi
Ronald E Gress
Naomi Taylor

Frontiers in Immunology

122 views

Editorial

Accepted on 17 Oct 2025

Editorial: Role of Tissue-Localized Regulatory T Cells in Health and Disease

in T Cell Biology

Bevin Smith
Diane Mathis Mathis
Ali A. Zarrin

Frontiers in Immunology

927 views

Original Research

Published on 17 Oct 2025

Altered Th17/Treg balance and therapeutic targeting of RORγ in primary focal hyperhidrosis

in T Cell Biology

Min Lin
Jianbo Lin
Quan Du
Yuanrong Tu
Jianfeng Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656632

749 views

Review

Published on 16 Oct 2025

Follicular helper T cells (Tfh): heterogeneity in spatial distribution and phenotypic characteristics

in T Cell Biology

Caifeng Shen
Qiong Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686687

698 views

Review

Accepted on 15 Oct 2025

Linking Epigenetic Mechanisms of T Cell Dysfunction with Pathophysiology of Type 1 Diabetes Mellitus

in T Cell Biology

Abdullah Jabri
Abdulrahman Elsalti
Mohamed Alsharif
Raghad Alsharif
Tasnim Abbad
Dania Alsibai
Bader Taftafa
Abdulaziz Mhannayeh
Mohammad Imran Khan
Ahmed Yaqinuddin

Frontiers in Immunology

203 views

Hypothesis and Theory

Published on 15 Oct 2025

The role of ubiquitin ligases in regulating immune cell functions

in T Cell Biology

Saci-Elodie Marty
Linda Yip
Fangyuan Wang
Manoj Kumar
C. Garrison Fathman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625419

436 views

Original Research

Published on 15 Oct 2025

Comparative immunophenotyping of peripheral blood lymphocyte subsets in pulmonary tuberculosis and nontuberculous mycobacterial pulmonary disease: a retrospective study

in T Cell Biology

Shuai Ren
Ruifang Chen
Ping Xu
Zhangyan Zhao
Haicheng Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682099

313 views

Original Research

Published on 15 Oct 2025

Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NFκB and NFAT pathways

in T Cell Biology

Karina M. Berschneider
Bernhard Wetterauer
Carsten Sticht
Christian Orlik
Beate Jahraus
Henning Kirchgessner
Anastasiia Zuieva
Stefan Wölfl
Divya Lairikyengbam
Verena Beier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655212

692 views

Review

Published on 14 Oct 2025

Thymus research in relation to myasthenia gravis: a new perspective on cell subpopulations and future directions

in T Cell Biology

Naoko Matsui
Izumi Ohigashi
Alexander Marx

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649171

750 views

Original Research

Published on 14 Oct 2025

Elevated Th1 and terminally differentiated cytotoxic T cells with suppressed Tc17 lymphocytes in lung tissue of advanced COPD and IPF patients undergoing lung transplantation

in T Cell Biology

Irena Šarc
Matija Rijavec
Luka Dejanović
Ana Koren
Matthias Zimmermann
Hendrik J. Ankersmit
Peter Korošec

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646711

1,715 views

Review

Published on 13 Oct 2025

Next-generation T cell immunotherapy: overcoming exhaustion, senescence, and suppression

in T Cell Biology

Guangmei Li
Dengju Li
Xiaojian Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662145

1,045 views

Mini Review

Accepted on 10 Oct 2025

Regulatory T Cell Therapies: From Patient Data to Biological Insights

in T Cell Biology

Kameron B Rodrigues
Peter J Eggenhuizen
Rosa Bacchetta
Zinaida Good

Frontiers in Immunology

306 views

Review

Published on 08 Oct 2025

Th17/Treg imbalance in inflammatory bowel disease: immunological mechanisms and microbiota-driven regulation

in T Cell Biology

Yuyuan Hu
Yuhang Yang
Yan Li
Qiang Zhang
Wei Zhang
Jinghan Jia
Zhuoyi Han
Jinxi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651063

2,461 views