Frontiers in Immunology

Review

Published on 28 May 2026

Multi-omics reveals circadian regulation of bone homeostasis by gut microbiota metabolites: mechanisms and chronotherapeutic implications

Mingdong Liu
Jiaqi Gong
Yaqi Liu
Jiayao Yu
Zepeng Hu
Zheng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719445

1,839 views
1 citation

Original Research

Published on 01 May 2026

Bioinformatics-driven insights: rapamycin-mediated CaMK2D inhibition alleviates intestinal ischemia-reperfusion injury

Ruxiang Sheng
Yanqiu Liang
Huihong Zhang
Yonghe Lai
Haiyun Hong
Dingbang Huang
Dezhao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684853

1,377 views

Review

Published on 01 Apr 2026

TWEAK-Fn14: a promising target for cardio-cerebrovascular diseases and brain-heart syndrome

Qinglin Fei
Jun Chang
Tingcan Jiang
Guoqiang Guan
Yujuan Liang
Cuicui Cheng
Guangxu Xiao
Qiuyan Guo
Guanwei Fan
Yan Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710055

2,047 views

Correction

Published on 27 Mar 2026

Correction: Anti-lipid IgG antibodies are produced via germinal centers in a murine model resembling human lupus

Carlos Wong-Baeza
Albany Reséndiz-Mora
Luis Donis-Maturano
Isabel Wong-Baeza
Luz Zárate-Neira
Juan Carlos Yam-Puc
Juana Calderón-Amador
Yolanda Medina
Carlos Wong
Isabel Baeza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711763

1,504 views

Review

Published on 24 Mar 2026

Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review

Mohamed T. El-Saadony
Ahmed M. Saad
Mahmoud Sitohy
Samar Sami Alkafaas
Mthokozisi Dladla
Soumya Ghosh
Dina Mostafa Mohammed
Essam H. Ibrahim
Mohamed A. Fahmy
Amr Elkelish

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713426

11,677 views
4 citations

Original Research

Published on 24 Mar 2026

Dietary Bazhen San solid-state fermentation product improves laying performance, immunity and intestinal health in laying hens during the late laying period

Zenghui Zhao
Xiao Wang
Yongzhan Bao
Jiahui Meng
Jinlong Gong
Lu Zhang
Zhaonian Li
Weiyu Yao
Yanan Chuo
Wanyu Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673604

1,672 views
2 citations

Original Research

Published on 18 Mar 2026

Neuronal autoantibodies associated with poorer neuropsychological and motor outcomes 6 months after stroke: results from the PHYS-STROKE trial

Charlotte Pietrock
Konrad Neumann
Kristin Rentzsch
Harald Prüss
Andreas Meisel
Matthias Endres
Alexander Heinrich Nave

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678840

1,412 views

Original Research

Published on 06 Mar 2026

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

Thomas Hutschalik
Albert Dasí
Leto L. Riebel
Maury Wiendels
Frederikus Bakker
Lucas J. A. M. Beckers
Koen C. Kriege
Susanne M. Valster
Roland C. M. Vulders
Ozan Özgül

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719392

2,257 views

Original Research

Published on 26 Feb 2026

Hepatic zinc deficiency dampens the acute phase response in patients with alcohol-associated hepatitis

Scott A. Read
Mehdi Ramezani-Moghadam
Brian S. Gloss
Romario Nguyen
Benjamin Woodham
Vincent Lam
Lawrence Yuen
Jimin Yoon
Liang Qiao
Thomas Tu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642163

2,348 views

Review

Published on 23 Feb 2026

A critical guideline for controlling monocyte-derived macrophages phenotypes

Giorgia Moschetti
Doriana Oliveri
Valeria De Matteis
Marta Zaccaria
Diego Rondelli
Anna Griego
Edoardo Scarpa
Loris Rizzello

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694625

4,266 views
2 citations

Perspective

Published on 23 Feb 2026

Hemophagocytic lymphohistiocytosis induced by immune checkpoint inhibitors: observations and proposed clinical management

Bianca Arianna Facchini
Benjamin Switzer
Marc S Ernstoff
Igor Puzanov
Paolo Antonio Ascierto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678966

3,086 views
2 citations

Review

Published on 20 Feb 2026

Immuno-neural mechanisms in gastrointestinal tumorigenesis: bridging inflammation, neural regulation, and therapeutic innovation

Yan Zhao
Ji-feng Sui
Dong-ning Wu
Min Chen
Jin-xia Ni
Yue Zhang
Shi-yong Xin
Meng-Nan Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682356

2,725 views
1 citation

Original Research

Published on 17 Feb 2026

Effect of pretransplant spleen volume on the prognosis of acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation

Weiwei Liu
Bingjie Liu
Lihou Pang
Lixia Zhou
Fuxu Wang
Xuejun Zhang
Ying Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675328

1,516 views

Original Research

Published on 13 Feb 2026

Transcriptomic profiling reveals distinct molecular signatures among lesion types in hidradenitis suppurativa

Hakim Ben Abdallah
Christine Daugaard
Louise Schøsler
Mads Kirchheiner Rasmussen
Line Kibsgaard
Trine Høgsberg
Claus Johansen
Trine Bertelsen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715474

2,614 views

Original Research

Published on 13 Feb 2026

Novel BPI3Vc-vectored surface displayed fusion and hemagglutinin-neuraminidase antigens elicit broadly neutralizing antibodies in cattle

Huldah Sang
Tae Kim
Rakshith Kumar
Jayden McCall
Aloysius Abraham
Tsvetoslav Koynarski
Michelle Zajac
Karim W. Abdelsalam
Daniela Hernandez Muguiro
Katherine Bauer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702440

2,043 views
1 citation

Original Research

Published on 12 Feb 2026

Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects

Paola Zelini
Federica Zavaglio
Mattia Dominoni
Marta Valsecchi
Lucrezia Lo Grasso
Piera d’Angelo
Federica Giardina
Greta Romano
Stefania Paolucci
Daniele Lilleri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733404

2,551 views

Original Research

Published on 12 Feb 2026

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

Veronika Ticha
Stepan Coufal
Zuzana Jiraskova Zakostelska
Tomas Thon
Radka Roubalova
Tomas Hrncir
Miloslav Kverka
Miluse Pavelcova
Pavlina Kleinova
Jana Lizrova Preiningerova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681342

2,722 views
1 citation

Review

Published on 12 Feb 2026

mRNA vaccines transform personalized lung cancer treatment

Kaiqi Wei
Zitong Wan
Miaomiao Wen
Shaowei Xin
Yinxi Zhou
Jun Wei
Jianfei Zhu
Chengbin Tang
Yanlu Xiong
Tao Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707654

6,285 views

Perspective

Published on 10 Feb 2026

From data to action: leveraging Global Burden of Disease Studies for rheumatic and musculoskeletal diseases

Shudan Chen
Yueyang Liu
Yu Xin
Yifan Qiu
Xuqiang Geng
Jiafeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1754256

1,621 views
1 citation

Original Research

Published on 10 Feb 2026

Long non-coding RNAs in response to Ebola virus vaccine-induced immunity

Izabela Mamede
Thomaz Luschër-Dias
Isabelle Franco Moscardini
Patrícia Gonzales-Dias
Bárbara Marinho
Fernando Marcon
Thiago Dominguez Crespo Hirata
Michael Eichberg
Donata Medaglini
Ali M. Harandi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1695514

2,851 views
1 citation

Review

Published on 10 Feb 2026

Urgent considerations on renal immune-related adverse events in oncology practice

Wen-Qing Lv
Jing-Yao Lu
Jun Li
Dao-Yuan Lv
Qi Ke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714090

2,034 views

Original Research

Published on 09 Feb 2026

Activation of NF-κB signaling in tissue-resident memory T cells promotes recurrent psoriasis in mice

Yukang Lin
Jiaying Chen
Han Du
Yuchao Chen
Zhaolin Liu
Xuejia Li
Yongdan Li
Feifei Qiu
Lingling Wen
Siyuan Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1762269

3,533 views
1 citation

Original Research

Published on 09 Feb 2026

Prognostic value of PD-L1 expression on tumor-infiltrating immune cells and neutrophil-to-lymphocyte ratio in patients with biliary tract cancer

Shang Chen
Guizhong Huang
Zehui Yao
Xiaojun Lin
Jianzhong Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729542

1,658 views

Original Research

Published on 09 Feb 2026

Unlocking binding properties of single-domain antibodies targeting the polymeric immunoglobulin receptor to enhance mucosal enrichment of IgG against respiratory syncytial virus

Jia Liu
Jiwon Jung
Siqun Zhou
Shi-Juan Chen
Jiping Huang
Yinyan Tang
Karin Vroom
Soha Motlagh
Daoyang Chen
Huong Trinh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1739562

2,625 views

7,283 Publications

volumes

Multi-omics reveals circadian regulation of bone homeostasis by gut microbiota metabolites: mechanisms and chronotherapeutic implications

Bioinformatics-driven insights: rapamycin-mediated CaMK2D inhibition alleviates intestinal ischemia-reperfusion injury

TWEAK-Fn14: a promising target for cardio-cerebrovascular diseases and brain-heart syndrome

Correction: Anti-lipid IgG antibodies are produced via germinal centers in a murine model resembling human lupus

Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review

Dietary Bazhen San solid-state fermentation product improves laying performance, immunity and intestinal health in laying hens during the late laying period

Neuronal autoantibodies associated with poorer neuropsychological and motor outcomes 6 months after stroke: results from the PHYS-STROKE trial

GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model

Hepatic zinc deficiency dampens the acute phase response in patients with alcohol-associated hepatitis

A critical guideline for controlling monocyte-derived macrophages phenotypes

Hemophagocytic lymphohistiocytosis induced by immune checkpoint inhibitors: observations and proposed clinical management

Immuno-neural mechanisms in gastrointestinal tumorigenesis: bridging inflammation, neural regulation, and therapeutic innovation

Effect of pretransplant spleen volume on the prognosis of acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation

Transcriptomic profiling reveals distinct molecular signatures among lesion types in hidradenitis suppurativa

Novel BPI3Vc-vectored surface displayed fusion and hemagglutinin-neuraminidase antigens elicit broadly neutralizing antibodies in cattle

Detection of human papillomavirus (HPV)-specific T cell response in women with low-grade cervical intraepithelial lesion and HPV vaccinated subjects

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

mRNA vaccines transform personalized lung cancer treatment

From data to action: leveraging Global Burden of Disease Studies for rheumatic and musculoskeletal diseases

Long non-coding RNAs in response to Ebola virus vaccine-induced immunity

Urgent considerations on renal immune-related adverse events in oncology practice

Activation of NF-κB signaling in tissue-resident memory T cells promotes recurrent psoriasis in mice

Prognostic value of PD-L1 expression on tumor-infiltrating immune cells and neutrophil-to-lymphocyte ratio in patients with biliary tract cancer

Unlocking binding properties of single-domain antibodies targeting the polymeric immunoglobulin receptor to enhance mucosal enrichment of IgG against respiratory syncytial virus