Frontiers in Medicine | Regulatory Science

Original Research

Accepted on 17 Sep 2025

A Model Structure for Describing Uncertainties in the Benefit Risk Assessment of Oncology Drug Applications

in Regulatory Science

Nikolaos Zafiropoulos
Francesco Pignatti
Andreas Kouroumalis
Lorenzo Guizzaro
Dominik Karres
Pierre Demolis
Olli Tenhunen
Rosanne Janssens
Anne Taams
Lourens Bloem

Frontiers in Medicine

doi 10.3389/fmed.2025.1589578

223 views

Original Research

Published on 17 Sep 2025

Performance analysis of EAC joint GMP inspections (2016–2022): a pathway to strengthening regulatory systems and building capacity in Africa’s less resourced authorities

in Regulatory Science

Jane Mashingia
Noel Aineplan
Kari Clase
Steven Bryn
Zita Ekeocha

Frontiers in Medicine

doi 10.3389/fmed.2025.1644446

597 views

Review

Published on 15 Sep 2025

Transforming the interrelated nature of human psychoneuroendocrine health and endocrine disrupting compounds in our planet’s water: from Wilhelm Waldeyer’s neuron theory to an artificial intelligence extension of the human body?

in Regulatory Science

Sophie Schweizer-Schubert
Götz von Waldeyer-Hartz
Susann-Elisabeth Schütze
Daniel Mahringer
Aki Sebastian Ruhl
Markus Graf
Jochen Kuckelkorn

Frontiers in Medicine

doi 10.3389/fmed.2025.1583203

479 views

Original Research

Accepted on 12 Sep 2025

Barriers and Determinants of Over-the-Counter Antibiotic Sales De-escalation: Perspectives of Community Pharmacists in Aseer, Saudi Arabia

in Regulatory Science

Sultan M. Alshahrani
Sirajudeen. S Alavudeen

Frontiers in Medicine

doi 10.3389/fmed.2025.1677246

500 views

Systematic Review

Accepted on 12 Sep 2025

of the Review: Concentration of Propolis as a Storage Medium for Avulsed Teeth: A Systematic Review

in Regulatory Science

Chaya Chhabra
Kumar Gaurav Chhabra
Dr Seemadevi T
Shraddha Shere

Frontiers in Medicine

doi 10.3389/fmed.2025.1583113

322 views

Systematic Review

Published on 11 Sep 2025

Visual analysis of quality management in Chinese drug clinical trials based on CiteSpace and COOC

in Regulatory Science

Jiayan Xia
Xuemei Ning
Lamei Jiang
Peipei Li
Jie Huang
Wenxiu Jiang
Wen Li
Cheng Wang
Linsha Zheng
Ting Jiang

Frontiers in Medicine

doi 10.3389/fmed.2025.1600915

950 views

Original Research

Published on 11 Sep 2025

Preparing for the European Health Data Space: an open-source compiler for fast, transparent, and portable health data transformations

in Regulatory Science

Stefan Beyer
Nikola Tanjga
Gabriel Kleinoscheg
Dieter Hayn
Klaus Donsa
Karl Kreiner
Günter Schreier

Frontiers in Medicine

doi 10.3389/fmed.2025.1661091

910 views

Systematic Review

Published on 10 Sep 2025

Societal participation in the development of orphan drugs: a systematic review

in Regulatory Science

Sanae Akodad
Delphine De Smedt
Hilde Stevens

Frontiers in Medicine

doi 10.3389/fmed.2025.1653304

900 views

Original Research

Accepted on 09 Sep 2025

Scientific and Regulatory Progress in Advancing Paediatric Oncology Drug Development in the EU and the US

in Regulatory Science

Giorgio Reggiardo
Alessandra Natale
Nicola Santoro
Viviana Giannuzzi
Claudia Pansieri
Mariagrazia Felisi
Donato Bonifazi
Adriana Ceci

Frontiers in Medicine

doi 10.3389/fmed.2025.1642279

213 views

Policy Brief

Published on 09 Sep 2025

Accelerating European electronic health record exchange format (EEHRxF) implementation across Europe: a policy perspective

in Regulatory Science

Nathan da Silva Carvalho
Alexia Papadimitriou
Robert Stegwee
Hans Gille
Michael Strübin
Christophe Maes
Giorgio Cangioli
Catherine Chronaki

Frontiers in Medicine

doi 10.3389/fmed.2025.1648170

975 views

Correction

Published on 05 Sep 2025

Correction: Summary of the best evidence for the use of antiseptics at various surgical sites to prevent postoperative infections

in Regulatory Science

Frontiers Production Office

Frontiers in Medicine

doi 10.3389/fmed.2025.1698325

474 views

Original Research

Published on 04 Sep 2025

Lessons from Ethiopian pharmaceutical regulation: a risk-based approach to overcome challenges and unlock opportunities

in Regulatory Science

Hassen Kebede Hassen
Yesuneh Tefera Mekasha
Addisu Afrassa Tegegne
Yildiz Ozalp

Frontiers in Medicine

doi 10.3389/fmed.2025.1484649

927 views

Original Research

Accepted on 03 Sep 2025

Considerations on the implementation of DCT: A SCAT-based analysis of fact-finding interviews in Europe and the United States, with implications for regions newly adopting DCT, including Japan

in Regulatory Science

Hiroyuki Taruno
Koji Ikeda
Marika Oikawa
Takahiro Sato
Yuka Suzuki
Mayumi Shikano

Frontiers in Medicine

doi 10.3389/fmed.2025.1521135

438 views

Perspective

Published on 02 Sep 2025

How life-cycle real-world evidence can bridge evidentiary gaps in precision oncology

in Regulatory Science

Emanuel Krebs
Deirdre Weymann
Tania Bubela
Dean A. Regier

Frontiers in Medicine

doi 10.3389/fmed.2025.1563950

1,124 views

Editorial

Published on 29 Aug 2025

Editorial: Errors and biases in modern healthcare: public health, medico-legal and risk management aspects

in Regulatory Science

Simone Grassi
Francesco Ausania
Davide Ferorelli
Francesco De Micco

Frontiers in Medicine

doi 10.3389/fmed.2025.1676522

771 views

Original Research

Published on 29 Aug 2025

Possibilities for secondary data use of electronic health records with WiseSpace de-identification

in Regulatory Science

Olga Vovk
Ali Ghasempour
Gunnar Piho
Peeter Ross

Frontiers in Medicine

doi 10.3389/fmed.2025.1639342

806 views