CORRECTION article

Front. Microbiol., 15 May 2019

Sec. Infectious Agents and Disease

Volume 10 - 2019 | https://doi.org/10.3389/fmicb.2019.01090

Corrigendum: Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice

  • 1. Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States

  • 2. Department of Biomedical Sciences, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States

In the original article, there was a mistake in the legend for Figure 6 as published. Figure 6 has 5 lanes, but only 4 are described in the legend. The lane that is not described is lane 3, which should list “3, F. novicida Δ1212–1218[1212-1213+].” As stated the description of lanes 3 and 4 are also wrong, as they should be listed as lanes 4 and 5. The correct legend appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

“Figure 6 | Carbohydrate and protein content of urea extracts from F. novicida and LVS strains. All strains were subcultured in CDMB and grown on CDMA at 32°C to enhance putative CLC production. The surface material was extracted using 1 M urea, and the crude CLC extracts were analyzed for carbohydrate content by the anthrone assay and for protein content by the BCA assay. The carbohydrate content of the extract from F. novicida Δ11212–1218_P10 contained significantly less carbohydrate than that of F. novicida_P10 (p = 0.02). The protein content between subcultured strains of F. novicida or between strains of LVS was not statistically different. Lanes: 1, F. novicida_P10; 2, F. novicida Δ11212–1218_P10; 3, F. novicida Δ1212–1218[1212–1213+]; 4, LVS_P10; 5, LVSΔ1422-1423_P10. Different letters above the bars indicate significant differences between the means when one-way ANOVA and Tukey's post-hoc were performed (p < 0.05). Identical uppercase letters indicate that there is no significant difference between the means. The value of bar marked with “A” is significantly different from the values of bars marked with “B” or “C.” The values of bars marked “AB” are not statistically different from the values of bars marked with “A” or with “B,” but are statistically different from a bar marked with “C.””

Summary

Keywords

Francisella novicida, capsule-like complex, virulence in mice, tularemia, glycosylation, protective immunity

Citation

Catanzaro KCF, Champion AE, Mohapatra N, Cecere T and Inzana TJ (2019) Corrigendum: Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice. Front. Microbiol. 10:1090. doi: 10.3389/fmicb.2019.01090

Received

29 April 2019

Accepted

30 April 2019

Published

15 May 2019

Approved by

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Volume

10 - 2019

Updates

Copyright

*Correspondence: Thomas J. Inzana

This article was submitted to Infectious Diseases, a section of the journal Frontiers in Microbiology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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