MINI REVIEW article
Front. Microbiol.
Sec. Microorganisms in Vertebrate Digestive Systems
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1554458
This article is part of the Research TopicNew Progress on the Role of Gut Microbiota in the Incidence and Prevention of Liver DiseasesView all 17 articles
Gut Microbiota and the "Gut-Liver-Kidney Axis" Theory: from mechanisms to therapeutics
Provisionally accepted
- 1Wenzhou Medical University, Wenzhou, China
- 2Sun Yat-sen University, Guangzhou, Guangdong Province, China
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The gut microbiota is essential for overall health, and in recent years, there has been increasing interest in its complex relationship with the "gut-liver-kidney axis." In this research, we aim to examine how the gut microbiota affects metabolic and immune responses via influencing the functions of the liver and kidneys. It will also analyze potential pathological mechanisms involved in this interaction and discuss therapeutic strategies that focus on modulating the gut microbiota.Through thoroughly reviewing existing literature, this article intends to offer fresh perspectives and insights that could inform future research and clinical applications in this rapidly developing area of study.
Keywords: Gut Microbiota, gut-liver-kidney axis, mechanisms, Therapeutics, Metabolism
Received: 02 Jan 2025; Accepted: 27 May 2025.
Copyright: © 2025 Fei, Liu, Liu, Yu and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ze Yu, Wenzhou Medical University, Wenzhou, China
Jin-Liang Dong, Wenzhou Medical University, Wenzhou, China
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