REVIEW article
Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1622394
This article is part of the Research TopicReviews in Molecular Evolution of Infectious Agents and DiseasesView all 6 articles
Advances in Research on Severe Fever with Thrombocytopenia Syndrome Virus
Provisionally accepted
- 1Department of Clinical Laboratory, Lu'an People's Hospital, Lu'an, China
- 2Department of Clinical Laboratory, Fuyang Second People's Hospital, Fuyang, China
- 3Department of Clinical Research, The 903rd Hospital of PLA, Hangzhou, China
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Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused by the SFTS virus (SFTSV). Since the first reported case, SFTSV has spread globally, particularly in Asian regions such as China, South Korea, and Japan, with an increasing number of cases and a high mortality rate among severe patients.SFTSV is an RNA virus capable of rapid biological evolution through genetic mutations, reassortment, and homologous recombination. The disease primarily occurs in mountainous, forested, and hilly areas. Due to limited clinical research, the clinical characteristics and pathogenesis of SFTS remain incompletely understood. This review summarizes recent advances in the regional epidemiological characteristics, clinical features, genotyping, pathogenesis, and rapid detection methods of SFTSV.
Keywords: Severe Fever with Thrombocytopenia Syndrome Virus, Genotype, Clinical features, Pathogenesis, Rapid detection
Received: 03 May 2025; Accepted: 11 Jul 2025.
Copyright: © 2025 YU, Li, Liu, Zhai, Dai and Lei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yuzhu Dai, Department of Clinical Research, The 903rd Hospital of PLA, Hangzhou, China
Sun Lei, Department of Clinical Laboratory, Lu'an People's Hospital, Lu'an, China
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