Frontiers in Molecular Biosciences

Methods

Published on 12 Feb 2026

Quantifying cytoskeletal protein interactions with far Western blotting

in Protein Biochemistry for Basic and Applied Sciences

Marcelo M. Melo
Elizabeth S. Phillippi
Mark L. Schultz
Susan Q. Shen
Hatem El-Shanti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1761723

173 views

Original Research

Published on 12 Feb 2026

Unlocking personalized endometrial cancer treatment: the critical role of the BBIRE biobank in sample collection and distribution

in Molecular Diagnostics and Therapeutics

V. Bruno
M. Betti
L. Ciuffreda
A. M. B. Arteni
M. Ferretti
F. Rossi
C. Accetta
C. Mandoj
V. Laquintana
F. De Nicola

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1748347

384 views

Original Research

Accepted on 11 Feb 2026

Integrative Transcriptomic Profiling of Tumor Patients in Surgical ICU: Identifying Prognostic Immune Signatures

in Molecular Diagnostics and Therapeutics

Changjin Chen
Hengquan Zhong
Songmao Ouyang
Jiying Lai
Chaoyu Wu

Frontiers in Molecular Biosciences

Original Research

Accepted on 11 Feb 2026

Disease classification via interpretable machine learning based on multi-center routine coagulation test

in Molecular Diagnostics and Therapeutics

Feng Dong
Yaqiong Zhang
Weibu Chen
Changmin Wang
Lei Zhang
Xiaoling Gao
Xiaoli Zhang
Minghua Jiang
Guobin Xu
Ruichuang Yang

Frontiers in Molecular Biosciences

Editorial

Accepted on 11 Feb 2026

Editorial: The role of calcium channels in human health and disease - Volume III

in Molecular Diagnostics and Therapeutics

Peng Zhang
Chang-Bo Zheng
Zhen Chen
Xiao-Yu Liu

Frontiers in Molecular Biosciences

Original Research

Published on 11 Feb 2026

Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory study

in Metabolomics

Huihui Wu
Hui Gao
Liang Guo
Xinyu Feng
Zhishen Zhang
Yiding Zhao
Haihong Chen
Zhi Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1743095

228 views

Editorial

Published on 11 Feb 2026

Editorial: Challenges and opportunities in tumor metabolomics

in Molecular Diagnostics and Therapeutics

Lei Yin
Cheng Kong
Chunmiao Cai
Hongqi Teng
Zhengyan Chang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1796372

160 views

Review

Published on 11 Feb 2026

Connecting the dots: deep learning-based automated model building methods in cryo-EM

in Structural Biology

Harsh Bansia
Amedee des Georges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1613399

712 views

Original Research

Accepted on 10 Feb 2026

Identification of core genes and transcription factors related to metabolic reprogramming in atherosclerosis: A multi-omics analysis and experimental validation approach

in Molecular Diagnostics and Therapeutics

Yanhong Liu
Yirong Ma
Zhijian Song
Junyu Lai
Yingying Huang
Doukun Ding
Zengguang Fan
Jianguang Wu

Frontiers in Molecular Biosciences

Original Research

Published on 10 Feb 2026

Identification of potential ferroptosis-related biomarkers in proliferative vitreoretinopathy based on machine learning

in RNA Networks and Biology

Jiangying Liu
Shengxiang Zhang
Lingdan Wu
Yingchao Xue
Boyu Liu
Hongyan Song
Qihua Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1725407

416 views

Original Research

Accepted on 09 Feb 2026

Identifying pyroptosis-related lncRNAs to predict prognosis and immune regulation in hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Wenjie Zhang
Yinjie Wang
Qiang Meng
Zhengcai Liu
Shibin Qu
Jingshi Zhou

Frontiers in Molecular Biosciences

Original Research

Accepted on 09 Feb 2026

Integrated bioinformatics and Mendelian randomization reveal a six-gene diagnostic signature and key role of CYP26B1 in sarcopenia

in Molecular Diagnostics and Therapeutics

Yaoqi Wu
Xiaoqing Cai
Shiwen Fan
Lina Zhao
Yingying Jiao
Tongkai Chen
Manting Liu
Yafang Song

Frontiers in Molecular Biosciences

Original Research

Published on 09 Feb 2026

Integrated network analysis and experimental validation identify CCNA2, CD44, and STAT1 as clinically relevant hub genes in oral squamous cell carcinoma

in Molecular Diagnostics and Therapeutics

Mingyang Bu
Yue Gu
Yuhan Meng
Yunyi Cui
Qianli Wu
Yali Kong
Haoyang Liu
Yi Chen
Jiajun Zhang
Lizhen Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1748821

372 views

Original Research

Published on 09 Feb 2026

Serum biomarker screening and metabolic profiling analysis of nonalcoholic fatty liver disease patients using untargeted metabolomics and machine learning techniques

in Metabolomics

Lijuan Dan
Huan Shi
Lina Cao
Xiuyan Li
Lirui Kong
Xiaojie You
Wenping Liu
Yanwei Hao
Dong Wang
Hongfei Song

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1730023

497 views

Original Research

Published on 09 Feb 2026

Single-cell RNA sequencing and integrated bioinformatics reveal new mitochondrial biomarkers in sarcopenia

in Metabolomics

Hongan Ying
Wenhan Wang
Lili Huang
Weiwen Hong
Lingchang Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1694362

353 views

Mini Review

Published on 09 Feb 2026

Histone methyltransferase SMYD1: playing a crucial role in disease progression

in Molecular Diagnostics and Therapeutics

Lingqian Duan
Yang Lou
Kan Huang
Kailing Pan
Xianguo Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1769660

257 views

Original Research

Published on 09 Feb 2026

Cuproptosis-related gene signatures define immune subtypes and predict prognosis in gastric cancer

in Molecular Diagnostics and Therapeutics

Zhe Wang
Yuxin Man
Bingtong Yue
Min Liu
Jiayi Zhang
Feng Wang
Dao Xin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1746613

314 views

Original Research

Published on 09 Feb 2026

Exploring the gut microbiota-microbial metabolites-targets regulatory network in metabolic dysfunction-associated steatotic liver disease

in Molecular Diagnostics and Therapeutics

Dapeng Yin
Wei Wu
Xiaojuan Wang
Junhua He
Yikun Zhu
Jin Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1764479

239 views

Review

Accepted on 06 Feb 2026

Succinylation: Novel Molecular Mechanisms and Prospects for Targeted Therapy in Liver Diseases

in Cellular Biochemistry

Jie Zhou
Xiaoling Tian
Yifang Zhou
Nianhua Tan
Bin Chen

Frontiers in Molecular Biosciences

Original Research

Accepted on 06 Feb 2026

HSF1 Modulates Lipid Metabolism and Ferroptosis in Sarcopenia: A Novel Diagnostic Biomarker and Therapeutic Target

in Molecular Diagnostics and Therapeutics

Dalu Cheng
Zhitao Shangguan
Xiaoqing Ye
Gang Chen
Qiong Lin
Jiandong Li

Frontiers in Molecular Biosciences

244 views

Review

Accepted on 06 Feb 2026

Novel Drugs Targeting Genetic Variants: Current Applications and Future Prospects in Heart Failure Treatment

in Molecular Diagnostics and Therapeutics

XIang Li
Suwen Bai
Yumei Luo

Frontiers in Molecular Biosciences

Original Research

Accepted on 06 Feb 2026

Construction of a Robust Sepsis Prognostic Classifier Based on E3 Ubiquitin Ligase-Related Genes

in Molecular Diagnostics and Therapeutics

Haiyan Xue
Lihe Chen
Xiujuan Zhao
Fengxue Zhu

Frontiers in Molecular Biosciences

Original Research

Published on 06 Feb 2026

Short-term continuous light exposure induces hippocampal rhythmic and functional alterations: a multi-timepoint metabolomics study

in Metabolomics

Xiuxuan Wu
Guanyu Zhang
Shuai Wu
Yuyu Hu
Yongqiang Zhang
Li Zhang
Xi Li
Jun Li
Danfeng Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1753977

463 views

Original Research

Accepted on 05 Feb 2026

Exploring hub genes related to adipocytokines in keloids: A combined analysis integrating single-cell, Mendelian randomization and bulk transcriptome data with experimental verification

in Protein Biochemistry for Basic and Applied Sciences

Maisude Mahemuti
Youyou Chen
Minxuan Li
Alimire Yilihamu

Frontiers in Molecular Biosciences

5,858 articles

articles

Quantifying cytoskeletal protein interactions with far Western blotting

Unlocking personalized endometrial cancer treatment: the critical role of the BBIRE biobank in sample collection and distribution

Integrative Transcriptomic Profiling of Tumor Patients in Surgical ICU: Identifying Prognostic Immune Signatures

Disease classification via interpretable machine learning based on multi-center routine coagulation test

Editorial: The role of calcium channels in human health and disease - Volume III

Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory study

Editorial: Challenges and opportunities in tumor metabolomics

Connecting the dots: deep learning-based automated model building methods in cryo-EM

Identification of core genes and transcription factors related to metabolic reprogramming in atherosclerosis: A multi-omics analysis and experimental validation approach

Identification of potential ferroptosis-related biomarkers in proliferative vitreoretinopathy based on machine learning

Identifying pyroptosis-related lncRNAs to predict prognosis and immune regulation in hepatocellular carcinoma

Integrated bioinformatics and Mendelian randomization reveal a six-gene diagnostic signature and key role of CYP26B1 in sarcopenia

Integrated network analysis and experimental validation identify CCNA2, CD44, and STAT1 as clinically relevant hub genes in oral squamous cell carcinoma

Serum biomarker screening and metabolic profiling analysis of nonalcoholic fatty liver disease patients using untargeted metabolomics and machine learning techniques

Single-cell RNA sequencing and integrated bioinformatics reveal new mitochondrial biomarkers in sarcopenia

Histone methyltransferase SMYD1: playing a crucial role in disease progression

Cuproptosis-related gene signatures define immune subtypes and predict prognosis in gastric cancer

Exploring the gut microbiota-microbial metabolites-targets regulatory network in metabolic dysfunction-associated steatotic liver disease

Succinylation: Novel Molecular Mechanisms and Prospects for Targeted Therapy in Liver Diseases

HSF1 Modulates Lipid Metabolism and Ferroptosis in Sarcopenia: A Novel Diagnostic Biomarker and Therapeutic Target

Novel Drugs Targeting Genetic Variants: Current Applications and Future Prospects in Heart Failure Treatment

Construction of a Robust Sepsis Prognostic Classifier Based on E3 Ubiquitin Ligase-Related Genes

Short-term continuous light exposure induces hippocampal rhythmic and functional alterations: a multi-timepoint metabolomics study

Exploring hub genes related to adipocytokines in keloids: A combined analysis integrating single-cell, Mendelian randomization and bulk transcriptome data with experimental verification