Frontiers in Molecular Biosciences

Editorial

Published on 31 Oct 2025

Editorial: Bioinformatics and systems biology strategies in disease management with a special emphasis on cancer, Alzheimer’s disease and aging

in Molecular Diagnostics and Therapeutics

Tiratha Raj Singh
Brigitte Vannier
Ragini Raj Singh
Hari Om Yadav
Holger Fröhlich

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1725000

192 views

Mini Review

Published on 31 Oct 2025

RNA-based therapies for neurodevelopmental disorders: innovative tools for molecular correction

in Molecular Diagnostics and Therapeutics

Denise Drongitis
Lucia Verrillo
Alberto de Bellis
Maria Giuseppina Miano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1681647

396 views

Original Research

Accepted on 30 Oct 2025

Visualizing mechanistic models by integrating site-specific molecular details into reaction networks

in Biological Modeling and Simulation

Dan Vasilescu
James C Schaff
Ion Moraru
Michael L Blinov

Frontiers in Molecular Biosciences

Perspective

Published on 30 Oct 2025

The sigma-1 receptor as a neurohomeostatic decision hub for GABARAP-mediated receptor trafficking and macroautophagy

in Cellular Biochemistry

Marius Wilhelm Baeken
Fazilet Bekbulat
Hagen Körschgen
Albrecht Martin Clement
Christian Behl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1673249

314 views

Review

Published on 30 Oct 2025

Immunological landscape of colorectal cancer: tumor microenvironment, cellular players and immunotherapeutic opportunities

in Molecular Diagnostics and Therapeutics

Adile Buse Andac-Aktas
Gizem Calibasi-Kocal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1687556

549 views

Original Research

Published on 30 Oct 2025

An exploratory study of urinary proteome in trigeminal neuralgia

in Metabolomics

Lilong Wei
Haitong Wang
Yun Zhou
Jianqiang Wu
Yongtong Cao
Yuliang Zhan
Youhe Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1618014

218 views

Original Research

Accepted on 29 Oct 2025

Investigating the molecular mechanisms of resveratrol in treating diabetic foot ulcers: a comprehensive analysis of network pharmacology and experiment validation

in Molecular Diagnostics and Therapeutics

Chao Sima
Zhe Wang
Sisi Wang
Haiyang Wang
Zhonghua Sun
Haoguo Wang
Daning Liang
Jianchi Li
Zhenning Zhang

Frontiers in Molecular Biosciences

171 views

Review

Accepted on 29 Oct 2025

SOX9: A Novel Janus-Faced Regulator in Immunity and Its Promise as a Therapeutic Target

in Molecular Diagnostics and Therapeutics

QIAN SHI
Shouyu He

Frontiers in Molecular Biosciences

Original Research

Accepted on 29 Oct 2025

A Prognostic Nomogram for Predicting Overall Survival in Gastric Signet Ring Cell Carcinoma Patients: a SEER Database and Chinese Registry Analysis

in Molecular Diagnostics and Therapeutics

Jie Wu
Jichen Wang
Ning Chen
Junjie Nie
Ling Xia
Quanpeng Li
Xueting Deng
Guozhong Ji

Frontiers in Molecular Biosciences

Original Research

Accepted on 29 Oct 2025

Prognostic model for lung adenocarcinoma based on experimental drug-resistant cell lines and clinical patients

in Molecular Diagnostics and Therapeutics

Jiasheng Zhang
Junnan Li
Xinyang Zhang
Chengwu Cao
Tianjie Zhou
Fengxian Liu
Hang Fai Kwok
Hui Zou
Liqing Hu

Frontiers in Molecular Biosciences

Original Research

Published on 29 Oct 2025

Decoding the anticancer and biofilm-inhibiting efficacy of Adansonia digitata using experimental, AI-powered, and molecular modeling approaches

in Biological Modeling and Simulation

Sangavi Pandi
Nachammai Kathiresan
Gowtham Kumar Subbaraj
Deepali Desai
Chitra Nagarajan
Langeswaran Kulanthaivel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1666360

346 views

Opinion

Published on 29 Oct 2025

The legacy of Bruce Ames and mitochondrial DNA mutagenicity: integrating oxidative stress, aging, and modern perspectives

in Cellular Biochemistry

Jennifer Dang
Jia Yu Liou
Rida Mullah
Cecilia Giulivi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1710944

404 views

Review

Published on 29 Oct 2025

Molecular mechanisms and computational insights into human SGLTs: advancing toward selective SGLT1 inhibition

in Structural Biology

Nadhiri Kaijage
Sebastian Kraszewski

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1668400

340 views

Original Research

Published on 29 Oct 2025

Identification and validation of mitochondrial-related genes in intestinal ischemia-reperfusion injury based on WGCNA and machine learning

in Molecular Diagnostics and Therapeutics

YiChen Hu
Jie Huang
XiaoLi Min
YuanPei Zhao
JiaHui Wang
HongYuan Liu
KaiWen Shi
WenLiang Li
WeiMing Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1691749

279 views

Review

Published on 29 Oct 2025

Niche-specific epigenetic interventions in the spatially heterogeneous glioblastoma microenvironmental landscape: strategies for radiotherapy enhancement

in Molecular Diagnostics and Therapeutics

Junjie Wang
Kunjie Li
Yongzhe Wang
Junyi Zhang
Xin Peng
Ning Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1704311

494 views

Editorial

Accepted on 28 Oct 2025

Editorial: Estrogens and Neurodegeneration – A Link Between Menopause and Alzheimer's Disease in Women

in Molecular Diagnostics and Therapeutics

Manuela Leri
Andrea Bertolini
Mario Lorenzo Díaz González
Roberta Marongiu

Frontiers in Molecular Biosciences

109 views