Frontiers in Molecular Neuroscience

Brief Research Report

Published on 18 Jun 2025

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability

in Molecular Signalling and Pathways

Annika Reisbitzer
Cecilia Hollitzer
Adriana Geraci
Jessye Schaefer
Maximilian Burghaus
Jonas Bruns
Joachim Urban
Thomas Kurz
Sybille Krauß

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1579194

2,482 views
1 citation

Brief Research Report

Published on 16 Jun 2025

SARS-CoV-2 viral proteins trigger pain via TLR2/4-MyD88 pathway

in Pain Mechanisms and Modulators

Wenliang Su
Xinrui Wang
Minghui Gu
Qiwei Zheng
Jiawen Yu
Dongliang Mu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1163636

2,377 views

Review

Published on 13 Jun 2025

Roles of ERK signaling pathway in regulating myelination of the peripheral nervous system

in Molecular Signalling and Pathways

Di Liu
Jingwei Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1617976

2,604 views
3 citations

Correction

Published on 09 Jun 2025

Corrigendum: Clinicopathological and molecular characterization of astroblastoma

in Molecular Signalling and Pathways

Xiaoyan Wu
Wenfeng Peng
Xu Zhang
Tao Tang
Ling Deng
Yuxia Xu
Xiaoyun Liu
Fang Wang
Wujian Peng
Jianrong Huang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1580624

1,420 views

Original Research

Published on 06 Jun 2025

Non-invasive biomarkers for brain aging: the role of autophagy-related microRNAs in plasma exosomes

in Molecular Signalling and Pathways

Qian Cheng
Shuyi Yu
Zhikang Cui
Hang Chen
Jing Fan
Qian Yu
Yan Jin
Yunshan Wang
Ming Li
Zhiming Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1588007

3,085 views
4 citations

Original Research

Published on 03 Jun 2025

A NaV1.8FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

in Pain Mechanisms and Modulators

John C. Y. Chen
Lech Kaczmarczyk
Walker S. Jackson
Max Larsson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1574219

2,127 views
3 citations

Original Research

Published on 27 May 2025

Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon

in Brain Disease Mechanisms

Robert A. Mans
Hannah Kelehear
Sarah Rotschafer
Clare Ganas
Brendan Uche-Moon
Gabrielle Call
Callie C. Mauersberg
Justin Toller
Andrew Diamanduros

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563086

3,492 views
3 citations

Review

Published on 21 May 2025

Chromatin modifiers in neurodevelopment

in Molecular Signalling and Pathways

Sarallah Rezazadeh
Hong Ji
Cecilia Giulivi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1551107

6,117 views
3 citations

Editorial

Published on 20 May 2025

Editorial: Molecular mechanisms of glutamatergic synapse function and dysfunction, volume II

in Molecular Signalling and Pathways

Dhrubajyoti Chowdhury
Jonathan G. Murphy

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1618161

1,770 views
1 citation

Original Research

Published on 20 May 2025

Potential therapeutic effects of ibudilast and retinoic acid against cuprizone-induced behavioral and biochemical changes in mouse brain

in Methods and Model Organisms

Kholoud A. Alyami
Gadah A. Alshahrany
Kholoud M. Al-Otaibi
Mohammad Z. Alam
Badrah S. Alghamdi
Hadeil M. Alsufiani
Nouf O. Alshareef
Hanna M. Alhoraibi
Sahar A. Alkhodair
Ulfat M. Omar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1567226

3,949 views

Original Research

Published on 20 May 2025

Exploring hypoxia-related genes in spinal cord injury: a pathway to new therapeutic targets

in Molecular Signalling and Pathways

Shihuan Cheng
Le Li
Mengmeng Xu
Ningyi Ma
Yinhua Zheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1565430

2,191 views

Mini Review

Published on 16 May 2025

Regulatory mechanism of circular RNAs in brain and neurodegenerative diseases

in Brain Disease Mechanisms

Mandana Amelimojarad
Melika Amelimojarad

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1507575

2,959 views
3 citations

Original Research

Published on 16 May 2025

Bidirectional substance P signaling between periodontal ligament fibroblasts and sensory neurons under mechanical stress

in Pain Mechanisms and Modulators

Judit Symmank
Lara Löffler
Ulrike Schulze-Späte
Collin Jacobs

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1583908

3,299 views
2 citations

Original Research

Published on 09 May 2025

Changes in glycinergic neurotransmission alter mammalian retinal information processing

in Brain Disease Mechanisms

Anneka Joachimsthaler
Katharina Hauf
Anja Armbruster
Shiri Zayit-Soudry
Efrat Naaman
Ido Perlman
Rina Leibu
Alina Kurolap
Hagit Baris Feldman
Jan Kremers

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564870

2,278 views
1 citation

Editorial

Published on 08 May 2025

Editorial: SLC12A5-dependent neurological disorders

in Brain Disease Mechanisms

Igor Medina
Amy McTague
Coralie Di Scala
Claudio Rivera

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1611682

2,162 views
1 citation

Review

Published on 08 May 2025

Current advances on RIPK2 and its inhibitors in pathological processes: a comprehensive review

in Molecular Signalling and Pathways

Shanshan Shen
Chen Lu
Tao Ling
Yanan Zheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1492807

7,122 views
3 citations

Review

Published on 02 May 2025

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

in Neuroplasticity and Development

Yinyi Xiong
Li Li
Xiaorong Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1575348

3,796 views
2 citations

Review

Published on 01 May 2025

NFE2L1 as a central regulator of proteostasis in neurodegenerative diseases: interplay with autophagy, ferroptosis, and the proteasome

in Brain Disease Mechanisms

Hossein Khodadadi
Kamila Łuczyńska
Dawid Winiarczyk
Paweł Leszczyński
Hiroaki Taniguchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1551571

4,590 views
7 citations

Original Research

Published on 30 Apr 2025

Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2

in Molecular Signalling and Pathways

Sheng Gong
Pan Wang
Bin Liao
Lu Zhao
Nan Wu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1584407

3,271 views
2 citations

Editorial

Published on 30 Apr 2025

Editorial: Neuro-immune interplay: unraveling the complexities of neurological complications and immunology

in Brain Disease Mechanisms

Pankaj Gaur
Kumar Vaibhav
Meenakshi Ahluwalia
Seema Gupta

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1607675

2,197 views
1 citation

Original Research

Published on 28 Apr 2025

Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples

in Brain Disease Mechanisms

Tommaso Livieri
Letizia Alfieri
Emiliana Giacomello
Djordje Alempijević
Tijana Petrovic
Yanko Georgiev Kolev
Davide Radaelli
Margherita Neri
Stefano D’Errico

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1562954

2,519 views

Brief Research Report

Published on 24 Apr 2025

Transcriptomic analysis of the TRP gene family in human brain physiopathology

in Molecular Signalling and Pathways

Barbara Olejniczak
Arpita Balakrishnan
Justyna Augustyniak
Elżbieta Salińska
Agnieszka Bronisz
Jakub Godlewski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1576941

2,491 views

Brief Research Report

Published on 17 Apr 2025

Expression of SUR1 isoforms in the brain and heart after ischemia/reperfusion

in Brain Disease Mechanisms

Iván Alquisiras-Burgos
Irlanda Peralta-Arrieta
Mónica Espinoza-Rojo
Alejandro Salazar-Salgado
Iván Antonino-Olguín
Alicia Sánchez-Mendoza
María Sánchez-Aguilar
Martha-Eugenia Ruiz-Tachiquín
Hilda-Alicia Valdez-Salazar
Alma Ortiz-Plata

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1536409

2,325 views

Original Research

Published on 16 Apr 2025

Redox homeostasis and inflammation in fibroblasts of patients with Friedreich Ataxia: a possible cross talk

in Molecular Signalling and Pathways

Andrea Quatrana
Sara Petrillo
Caterina Torda
Eleonora De Santis
Enrico Bertini
Fiorella Piemonte

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1571402

2,868 views
3 citations

4,351 articles

articles

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability

SARS-CoV-2 viral proteins trigger pain via TLR2/4-MyD88 pathway

Roles of ERK signaling pathway in regulating myelination of the peripheral nervous system

Corrigendum: Clinicopathological and molecular characterization of astroblastoma

Non-invasive biomarkers for brain aging: the role of autophagy-related microRNAs in plasma exosomes

A NaV1.8FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon

Chromatin modifiers in neurodevelopment

Editorial: Molecular mechanisms of glutamatergic synapse function and dysfunction, volume II

Potential therapeutic effects of ibudilast and retinoic acid against cuprizone-induced behavioral and biochemical changes in mouse brain

Exploring hypoxia-related genes in spinal cord injury: a pathway to new therapeutic targets

Regulatory mechanism of circular RNAs in brain and neurodegenerative diseases

Bidirectional substance P signaling between periodontal ligament fibroblasts and sensory neurons under mechanical stress

Changes in glycinergic neurotransmission alter mammalian retinal information processing

Editorial: SLC12A5-dependent neurological disorders

Current advances on RIPK2 and its inhibitors in pathological processes: a comprehensive review

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

NFE2L1 as a central regulator of proteostasis in neurodegenerative diseases: interplay with autophagy, ferroptosis, and the proteasome

Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2

Editorial: Neuro-immune interplay: unraveling the complexities of neurological complications and immunology

Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples

Transcriptomic analysis of the TRP gene family in human brain physiopathology

Expression of SUR1 isoforms in the brain and heart after ischemia/reperfusion

Redox homeostasis and inflammation in fibroblasts of patients with Friedreich Ataxia: a possible cross talk