Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 28 Apr 2025

Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples

in Brain Disease Mechanisms

Tommaso Livieri
Letizia Alfieri
Emiliana Giacomello
Djordje Alempijević
Tijana Petrovic
Yanko Georgiev Kolev
Davide Radaelli
Margherita Neri
Stefano D’Errico

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1562954

124 views

Original Research

Accepted on 24 Apr 2025

Changes in glycinergic neurotransmission alters mammalian retinal information processing

in Brain Disease Mechanisms

Anneka Joachimsthaler
Katharina Hauf
Anja Armbruster
Shiri Zayit -Soudry
Efrat Naaman
Ido Perlman
Rina Leibu
Alina Kurolap
Hagit Baris-Feldman
Jan Kremers

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564870

Original Research

Accepted on 23 Apr 2025

Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon 6106 Words; 5 Figures

in Brain Disease Mechanisms

Robert Alan Mans
Hannah Kelehear
Sarah Rotschafer
Clare Ganas
Brendan Uche- Moon
Gabrielle Call
Callie Mauersberg
Justin Toller
Andy Diamonduros

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563086

134 views

Editorial

Accepted on 21 Apr 2025

Editorial: SLC12A5-Dependent Neurological Disorders-From Bench to Bedside

in Brain Disease Mechanisms

Igor Medina
Claudio Rivera
Coralie Di Scala
Amy McTague

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1611682

Brief Research Report

Published on 17 Apr 2025

Expression of SUR1 isoforms in the brain and heart after ischemia/reperfusion

in Brain Disease Mechanisms

Iván Alquisiras-Burgos
Irlanda Peralta-Arrieta
Mónica Espinoza-Rojo
Alejandro Salazar-Salgado
Iván Antonino-Olguín
Alicia Sánchez-Mendoza
María Sánchez-Aguilar
Martha-Eugenia Ruiz-Tachiquín
Hilda-Alicia Valdez-Salazar
Alma Ortiz-Plata

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1536409

325 views

Original Research

Published on 15 Apr 2025

Brain microvascular endothelial cells differentiated from a Friedreich’s Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeable

in Brain Disease Mechanisms

Frances M. Smith
Daniel J. Kosman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1511388

379 views

Editorial

Accepted on 09 Apr 2025

Editorial: "Neuro-Immune Interplay: Unraveling the Complexities of Neurological Complications and Immunology"

in Brain Disease Mechanisms

Pankaj Gaur
Kumar Vaibhav
Meenakshi Ahluwalia
Seema Gupta

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1607675

187 views

Original Research

Published on 09 Apr 2025

Profiling the expression and functional roles of mRNAs and lncRNAs associated with post-stroke aphasia

in Brain Disease Mechanisms

Yanling Xi
Hui Chang
Mei Qu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1513218

294 views

Mini Review

Accepted on 07 Apr 2025

Regulatory mechanism of circular RNAs in brain and neurodegenerative diseases

in Brain Disease Mechanisms

Mandana AmeliMojarad
Melika Amelimojarad

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1507575

Mini Review

Published on 01 Apr 2025

Neurotrophic factor alpha 1 gene therapy in Alzheimer’s disease: scope and advancements

in Brain Disease Mechanisms

Ammara Shaikh
Fairus Ahmad
Seong Lin Teoh
Jaya Kumar
Mohamad Fairuz Yahaya

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1518868

1,004 views

Original Research

Published on 24 Mar 2025

The serum proteomic profile in patients with migraine

in Brain Disease Mechanisms

Yating Han
Yuan Wang
Xiajuan Zou
Huailian Guo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1460403

715 views

Original Research

Published on 21 Mar 2025

Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice

in Brain Disease Mechanisms

Cara J. Westmark

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1520211

837 views

Mini Review

Published on 19 Mar 2025

Elevated propionate and its association with neurological dysfunctions in propionic acidemia

in Brain Disease Mechanisms

Xiaoxin Chen
Qing Cheng
Guo-Fang Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1499376

765 views

Review

Accepted on 14 Mar 2025

NFE2L1 as a Central Regulator of Proteostasis in Neurodegenerative Diseases: Interplay with Autophagy, Ferroptosis, and the Proteasome

in Brain Disease Mechanisms

Hossein Khodadadi
Kamila Łuczyńska
Dawid Winiarczyk
Paweł Leszczyński
Hiroaki Taniguchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1551571

131 views

Original Research

Published on 04 Mar 2025

Bioenergetic-related gene expression in the hippocampus predicts internalizing vs. externalizing behavior in an animal model of temperament

in Brain Disease Mechanisms

Elaine K. Hebda-Bauer
Megan H. Hagenauer
Daniel B. Munro
Peter Blandino
Fan Meng
Keiko Arakawa
John D. H. Stead
Apurva S. Chitre
A. Bilge Ozel
Pejman Mohammadi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1469467

1,082 views
1 citation

Original Research

Published on 20 Feb 2025

Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegeneration in spastic ataxia type 5

in Brain Disease Mechanisms

Menekse Oeztuerk
Diran Herebian
Kale Dipali
Andreas Hentschel
Nina Rademacher
Florian Kraft
Rita Horvath
Felix Distelmaier
Sven G. Meuth
Tobias Ruck

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1548255

994 views