Frontiers in Molecular Neuroscience | Pain Mechanisms and Modulators

Original Research

Published on 16 May 2025

Bidirectional substance P signaling between periodontal ligament fibroblasts and sensory neurons under mechanical stress

in Pain Mechanisms and Modulators

Judit Symmank
Lara Löffler
Ulrike Schulze-Späte
Collin Jacobs

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1583908

201 views

Original Research

Accepted on 12 May 2025

A NaV1.8 FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

in Pain Mechanisms and Modulators

John CY Chen
Lech Kaczmarczyk
Walker Scot Jackson
Max Larsson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1574219

Mini Review

Published on 21 Mar 2025

Environmental enrichment for neuropathic pain via modulation of neuroinflammation

in Pain Mechanisms and Modulators

Jian-Dong Zhang
Zi-An Zhong
Wen-Yuan Xing

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1547647

1,050 views

Systematic Review

Published on 24 Dec 2024

Mapping the research landscape of microRNAs in pain: a comprehensive bibliometric analysis

in Pain Mechanisms and Modulators

Huaiming Wang
Qin Li
Jiang Zou
Jinjun Shu
Aimin Zhang
Hongwei Zhang
Qi Zhao
Shunxin Liu
Chan Chen
Guo Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1493822

1,435 views

Systematic Review

Published on 16 Oct 2024

Ziconotide and psychosis: from a case report to a scoping review

in Pain Mechanisms and Modulators

Marc Peraire
Rita Gimeno-Vergara
Jennifer Pick-Martin
Mireia Boscá
Iván Echeverria

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1412855

1,465 views

Original Research

Published on 02 Oct 2024

Molecular determinants of resurgent sodium currents mediated by Navβ4 peptide and A-type FHFs

in Pain Mechanisms and Modulators

Yucheng Xiao
Yanling Pan
Jingyu Xiao
Theodore R. Cummins

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1433981

1,448 views

Original Research

Published on 02 Oct 2024

Risk factors for poor prognosis in patients with zoster-associated neuralgia who underwent interventional pain management

in Pain Mechanisms and Modulators

Junpeng Yuan
Youjia Yu
Hong Liu
Huichan Xu
Yan Li
Xiaohong Jin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1393219

1,079 views

Editorial

Published on 16 Sep 2024

Editorial: Molecular neurobiology of chronic pain: pharmacological and non-pharmacological approaches in animal models

in Pain Mechanisms and Modulators

Mario A. Acuña
Kristina Valentinova
Pascal Darbon

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1487141

882 views

Editorial

Published on 12 Sep 2024

Editorial: Molecular mechanism of neuroimmune modulation and synaptic plasticity in acute and chronic pain, volume II

in Pain Mechanisms and Modulators

Shunmei Lu
Yuxin Zhang
Zilong Wang
Linlin Zhang
Xin Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1484826

904 views

Review

Published on 10 Sep 2024

A cutting-edge new framework for the pain management in children: nanotechnology

in Pain Mechanisms and Modulators

Iuliana Magdalena Starcea
Ancuta Lupu
Ana Maria Nistor
Maria Adriana Mocanu
Roxana Alexandra Bogos
Alice Azoicai
Diana Cira
Madalina Beldie
Vasile Valeriu Lupu
Ionela Daniela Morariu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1391092

1,364 views

Review

Published on 09 Sep 2024

The dual role of TRPV1 in peripheral neuropathic pain: pain switches caused by its sensitization or desensitization

in Pain Mechanisms and Modulators

Ning Gao
Meng Li
Weiming Wang
Zhen Liu
Yufeng Guo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1400118

6,321 views
5 citations

Original Research

Published on 03 Sep 2024

Reward system neurodynamics during menstrual pain modulated by COMT Val158Met polymorphisms

in Pain Mechanisms and Modulators

Pei-Shan Hsu
Ching-Hsiung Liu
Ching-Ju Yang
Lin-Chien Lee
Wei-Chi Li
Hsiang-Tai Chao
Ming-Wei Lin
Li-Fen Chen
Jen-Chuen Hsieh

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1457602

1,796 views

Original Research

Published on 30 Aug 2024

Dock4 contributes to neuropathic pain by regulating spinal synaptic plasticity in mice

in Pain Mechanisms and Modulators

Qiaochu Fu
Hongyi Li
Zhuanxu Zhu
Wencui Li
Zhihua Ruan
Ruijie Chang
Huixia Wei
Xueqin Xu
Xunliang Xu
Yanqiong Wu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1417567

1,731 views

Original Research

Published on 06 Aug 2024

Coordination between midcingulate cortex and retrosplenial cortex in pain regulation

in Pain Mechanisms and Modulators

Yunya Qiu
Yan-Na Lian
Cheng Wu
Li Liu
Chen Zhang
Xiang-Yao Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1405532

1,369 views
1 citation

Original Research

Published on 17 Jul 2024

Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels

in Pain Mechanisms and Modulators

Gerald Z. Zhuang
William F. Goins
Munal B. Kandel
Marco Marzulli
Mingdi Zhang
Joseph C. Glorioso
Yuan Kang
Alexandra E. Levitt
Konstantinos D. Sarantopoulos
Roy C. Levitt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1416148

2,247 views
1 citation

Mini Review

Published on 26 Jun 2024

Treadmill running on neuropathic pain: via modulation of neuroinflammation

in Pain Mechanisms and Modulators

Wei-Chun He
Shuang-Long Hou
Kai-Bin Wang
Ning Xu
Ke Li
Ting Xiong
Jing Luo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1345864

2,377 views