Frontiers in Neurology

Study Protocol

Published on 28 Oct 2025

Targeting the gut to improve seizure control in CDKL5 deficiency disorder (CDD): study protocol for a single-arm, open-label clinical trial

in Epilepsy

Francesca Triva
Elisa Borghi
Matteo Domenico Marsiglia
Emerenziana Ottaviano
Emilia Ricci
Paola Tognini
Marco Montecucco
Aglaia Vignoli

Frontiers in Neurology

doi 10.3389/fneur.2025.1642329

398 views

Original Research

Accepted on 27 Oct 2025

Exploratory Analysis of Epilepsy Biomarkers Using Untargeted Metabolomics Across Multiple Cohorts

in Epilepsy

Kaisa Teele Oja
Mihkel Ilisson
Karit Reinson
Kai Muru
Tiia Reimand
Hedi Peterson
Dmytro Fishman
Toomas Haller
Jaanika Kronberg
Estonian Biobank Research Team

Frontiers in Neurology

202 views

Original Research

Published on 23 Oct 2025

Preserved ictal responsiveness in right mesial temporal lobe epilepsy: metabolic correlates in posterior temporal networks with FDG-PET

in Epilepsy

Yi-Seul Choo
Young-Min Shon
Seung Hwan Moon
Jeongsik Kim
Hea Ree Park
Eun Yeon Joo
Dae Won Seo

Frontiers in Neurology

doi 10.3389/fneur.2025.1690510

436 views

Original Research

Accepted on 22 Oct 2025

Assessment of a Biometric Shirt for Sleep Body Position Identification in Epilepsy

in Epilepsy

Emmanuelle Nguyen
Manon Robert
Tian Yue Ding
Oumayma Gharbi
Amirhossein Jahani
Jérôme St-Jean
Claudia Rodriguez
Isabel Sarzo Wabi
Daniel Alejandro Galindo Lazo
Dang Khoa Nguyen

Frontiers in Neurology

490 views

Original Research

Published on 22 Oct 2025

Unsupervised clustering of pre-ictal EEG in children: a reproducible and lightweight CPU-based workflow

in Epilepsy

Ahmad A. Jiman
Eyad Talal Attar

Frontiers in Neurology

doi 10.3389/fneur.2025.1665008

856 views

Correction

Published on 21 Oct 2025

Correction: Study on brain functional networks and wearable device monitoring in children with SeLECTs and high spike-wave index (SWI >50%)

in Epilepsy

Minghao Xu
Xiaoxuan Li
Yifan Fu
Dinghan Hu
Yang Zhang
Wang Wei
Yaotian Gao
Keyi Lin
Bin Yang
Jiuwen Cao

Frontiers in Neurology

doi 10.3389/fneur.2025.1719076

321 views

Brief Research Report

Accepted on 20 Oct 2025

Dynamic Astrocytic complement C3 Activation in the Epileptic Hippocampus

in Epilepsy

Mi Jiang
Alessia Romagnolo
Eleonora Aronica
Yu Wang

Frontiers in Neurology

106 views

Original Research

Accepted on 13 Oct 2025

Benzodiazepines versus non-benzodiazepine antiseizure medications as first-line agents for status epilepticus: analysis of real word data from a 9-years prospective cohort

in Epilepsy

Francesco Brigo
Gianni Turcato
Giada Giovannini
Simona Lattanzi
Arian Zaboli
Niccolò Orlandi
Margherita Burani
Lisa Taruffi
Leonardo Affronte
Stefano Meletti

Frontiers in Neurology

186 views

Systematic Review

Published on 10 Oct 2025

Seizure outcomes and complications associated with stereoelectroencephalography versus subdural electrodes for invasive monitoring in epilepsy surgery: a meta-analysis

in Epilepsy

Nallammai Muthiah
Hope M. Reecher
Seyed Farzad Maroufi
Alireza Mansouri
Emily Harford
Taylor J. Abel

Frontiers in Neurology

doi 10.3389/fneur.2025.1619288

1,268 views

Original Research

Published on 10 Oct 2025

Prevalence, severity, frequency and healthcare resource use of epilepsy among individuals with Rett Syndrome: analysis of data from a Rett Center of Excellence

in Epilepsy

Nazia Rashid
Charles Ruetsch
Emily M. LaFrance
Jonathan D. Darer

Frontiers in Neurology

doi 10.3389/fneur.2025.1634105

1,364 views

Original Research

Published on 09 Oct 2025

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

in Epilepsy

Raniah Ibrahim Aljadeed
Amenah Alkaf
Daad Alhajlbrahim
Huda Alewairdhi
Ghadah Asaad Assiri
Rana Aljadeed
Haya Almalag
Nora Kalagi

Frontiers in Neurology

doi 10.3389/fneur.2025.1645435

932 views

Original Research

Published on 07 Oct 2025

Innovating the practice of epilepsy care to improve patient outcomes: a model for community health worker integration

in Epilepsy

Elaine T. Kiriakopoulos
Felicia Chu
Barbara C. Jobst
Rosemarie Kobau

Frontiers in Neurology

doi 10.3389/fneur.2025.1654687

1,876 views

Original Research

Published on 07 Oct 2025

Add-on ketogenic diet versus antiseizure medications alone in children with developmental and epileptic encephalopathies: a prospective comparative cohort study

in Epilepsy

Wandong Hu
Lili Li
Fen Zhao
Song Su
Hongwei Zhang
Xiaoying Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1677046

1,069 views

Original Research

Accepted on 06 Oct 2025

Combined MRI Morphometry and Source Imaging Guides Placement of Stereo-EEG Electrodes in Focal Epilepsy with Subtle or Absent Lesions

in Epilepsy

Peter C. Reinacher
Dirk-Matthias Altenmüller
Julia M. Nakagawa
Yiwen Li Hegner
Cristian Dorign Antal
Matthias Duempelmann
Theo Demerath
Anke Maren Staack
Hans-Jürgen Huppertz
Soroush Doostkam

Frontiers in Neurology

274 views

Original Research

Published on 30 Sep 2025

Study on brain functional networks and wearable device monitoring in children with SeLECTs and high spike-wave index (SWI >50%)

in Epilepsy

Minghao Xu
Xiaoxuan Li
Yifan Fu
Dinghan Hu
Yang Zhang
Wang Wei
Yaotian Gao
Keyi Lin
Bin Yang
Jiuwen Cao

Frontiers in Neurology

doi 10.3389/fneur.2025.1571330

1,118 views

Brief Research Report

Published on 29 Sep 2025

Postictal punctate hippocampal diffusion restriction: the chicken or the egg?

in Epilepsy

Jan Heckelmann
Yvonne Weber
Manuel Dafotakis
Stefan Wolking

Frontiers in Neurology

doi 10.3389/fneur.2025.1659610

1,859 views