In the published article, an error occurred in the representative immunoblot plot of TH in Figure 2B and Figure 8. The corrected Figure 2 and Figure 8 appear below.
Figure 2
SIRT4 plays a role in a PD model. (A) Flow chart of stereotactic injection of SIRT4-AAV virus and the establishment of a mouse model of PD induced by MPTP. (B) Representative western blots and densitometric analysis for TH protein between groups. TH protein extracts from substantia nigra after mice were intraperitoneally injected with saline and MPTP for 5 days. GAPDH was used as a loading control (n = 4 mice per group). (C) Representative western blots and densitometric analysis for SIRT4 protein between groups. SIRT4 protein extracts from substantia nigra after mice were intraperitoneally injected with saline or MPTP for 5 days. Tubulin was used as a loading control (n = 4 mice per group). (D, E) Representative western blots and densitometric analysis for DJ-1 or SIRT4 protein between groups, respectively. DJ-1 or SIRT4 protein extracts from substantia nigra of WT rats or DJ-1 KO rats. Tubulin was used as a loading control (n = 4 mice per group). All results are depicted as means ± SEM. The comparison across groups was analyzed by t-test. **P < 0.01, ***P < 0.001, and ****P < 0.0001 compared with the control group. TH, tyrosine hydroxylase; SIRT4, NAD-dependent protein lipoamidase sirtuin-4, mitochondrial.
Figure 8
Data visualizations of the results from the KEGG enrichment analysis of differentially expressed genes and proteins in SH-SY5Y cells after SIRT4 overexpression with ClueGO. A KEGG enrichment analysis of differentially expressed proteins in SH-SY5Y cells after SIRT4 overexpression was performed using ClueGO. The figure clearly shows the main proteins in the enriched pathways and the connection between A protein and different pathways. The size of the circle represents the number of different proteins.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Publisher’s note
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Summary
Keywords
Parkinson's disease, SIRT4, quantitative proteomic analysis, bioinformatics, biomarkers, FABP4, PPAR signaling pathway
Citation
Weng H, Song W, Fu K, Guan Y, Cai G, Huang E, Chen X, Zou H and Ye Q (2023) Corrigendum: Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's mouse model. Front. Neurosci. 17:1201109. doi: 10.3389/fnins.2023.1201109
Received
06 April 2023
Accepted
08 November 2023
Published
23 November 2023
Volume
17 - 2023
Edited and reviewed by
Wen-Jun Tu, Chinese Academy of Medical Sciences and Peking Union Medical College, China
Updates
Copyright
© 2023 Weng, Song, Fu, Guan, Cai, Huang, Chen, Zou and Ye.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Qinyong Ye unionqyye@163.comHaiqiang Zou dr_zou@163.com
†These authors have contributed equally to this work and share first authorship
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.