Frontiers in Neuroscience | Gut-Brain Axis

Mini Review

Published on 14 Feb 2025

The brain-gut axis and chronic pain: mechanisms and therapeutic opportunities

in Gut-Brain Axis

Tim Ho
Ömer Elma
Lucy Kocanda
Katherine Brain
Thao Lam
Tejas Kanhere
Huan-Ji Dong

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1545997

10,040 views
11 citations

Review

Published on 06 Feb 2025

Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression

in Gut-Brain Axis

Amanda Gollo Bertollo
Camila Ferreira Santos
Margarete Dulce Bagatini
Zuleide Maria Ignácio

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1541075

26,845 views
50 citations

Original Research

Published on 04 Feb 2025

Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice

in Gut-Brain Axis

Ning Ding
Xin Hao
Yue Zhang
Yanxiang Zhang
Zhigang Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1509581

2,853 views
5 citations

Mini Review

Published on 04 Feb 2025

Alzheimer's disease and gut-brain axis: Drosophila melanogaster as a model

in Gut-Brain Axis

Samuel de Mattos Alves
Paulo Noronha Lisboa-Filho
Carolina Letícia Zilli Vieira
Marina Piacenti-Silva

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1543826

5,947 views
4 citations

Original Research

Published on 29 Jan 2025

Effects of repeated intragastric administrations with heat-inactivated Mycobacterium aurum DSM 33539 on the stress-induced aggravation of dextran sulfate sodium (DSS) colitis in C57BL/6N mice

in Gut-Brain Axis

Dominik Langgartner
Anna-Lena J. Weiss
Mattia Amoroso
John D. Sterrett
Christopher A. Lowry
Stefan O. Reber

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1488603

2,903 views
3 citations

Clinical Trial

Published on 07 Jan 2025

Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial

in Gut-Brain Axis

Robin M. Voigt
Phillip A. Engen
Michelle Villanueva
Simona A. Bambi
Stefan J. Green
Ankur Naqib
Shohreh Raeisi
Maliha Shaikh
Bruce R. Hamaker
Thaisa M. Cantu-Jungles

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1477519

4,122 views
7 citations

Review

Published on 23 Dec 2024

Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome

in Gut-Brain Axis

Xinlei Dong
Xiaomin Hao
Jian Wen
Qinfeng Yan
Kaixuan Ma
Qingguo Liu
Juan Li
Lili Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1495384

3,750 views
3 citations

Original Research

Published on 11 Dec 2024

Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research

in Gut-Brain Axis

Rossitza Draganova
Genisius Hartanto
Robert Jan Pawlik
Jana Luisa Aulenkamp
Sigrid Elsenbruch

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1502752

2,084 views
1 citation

Review

Published on 09 Dec 2024

Mechanisms of microbiota-gut-brain axis communication in anxiety disorders

in Gut-Brain Axis

Min Jiang
Li Kang
Ya-Li Wang
Bin Zhou
Hong-Yi Li
Qiang Yan
Zhi-Gang Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1501134

10,539 views
14 citations

Review

Published on 03 Dec 2024

Using lifestyle interventions and the gut microbiota to improve PTSD symptoms

in Gut-Brain Axis

Steven G. Sugden
Gia Merlo

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1488841

5,177 views
4 citations

Systematic Review

Published on 02 Dec 2024

Alterations of fractional anisotropy and white matter integrity in irritable bowel syndrome: a systematic review and meta-analysis of diffusion tensor imaging studies

in Gut-Brain Axis

Mahsa Asadi Anar
Aydin Hassanpour Adeh
Samira Peiravi
Alireza Imani Porshokouh
Seyedeh Sara Rezazadeh Shojaee
Farnaz Najafi
Yasamin Pishkari
Arash Rahimi
Shaghayegh Karami

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1426218

2,823 views
3 citations

Review

Published on 26 Nov 2024

Roles of the gut microbiota in human neurodevelopment and adult brain disorders

in Gut-Brain Axis

Rahul Mallick
Sanjay Basak
Ranjit K. Das
Antara Banerjee
Sujay Paul
Surajit Pathak
Asim K. Duttaroy

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1446700

7,479 views
11 citations

Review

Published on 15 Nov 2024

Aberrant intrinsic brain activities in functional gastrointestinal disorders revealed by seed-based d mapping with permutation of subject images

in Gut-Brain Axis

Yibin Shuai
Benhong Wang
Xiaomei Zhang
Zhongxia Shen
Shengbo Han
Cong Zhou

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1452216

2,881 views
4 citations

Original Research

Published on 06 Nov 2024

Cognotoxemia: endotoxemia and gender predict changes in working memory performance in healthy adults

in Gut-Brain Axis

Sally C. McDonnell
Jennifer E. Graham-Engeland
Martin J. Sliwinski
Christopher G. Engeland
Erik L. Knight

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1453325

1,876 views
1 citation

Original Research

Published on 11 Oct 2024

Integrated gut microbiome and metabolomic analyses elucidate the therapeutic mechanisms of Suanzaoren decoction in insomnia and depression models

in Gut-Brain Axis

Hongxiong Zhang
Taixiang Gao
Feng Zhao
Nan Wang
Zhixuan Li
Xuemei Qin
Ying Liu
Rui Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1459141

4,553 views
4 citations

Review

Published on 26 Sep 2024

The role of the gut microbiota in neurodegenerative diseases targeting metabolism

in Gut-Brain Axis

Yufeng Fu
Zhongya Gu
Huan Cao
Chengchao Zuo
Yaqi Huang
Yu Song
Yongsheng Jiang
Furong Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1432659

5,526 views
7 citations

Original Research

Published on 20 Sep 2024

Gut microbiota-derived acetate promotes long-term recovery through angiogenesis guided by lymphatic ingrowth in older adults with stroke

in Gut-Brain Axis

Yujia Yuan
Linlin Li
Jingjing Wang
Bat-Otgon Myagmar
Yuxiao Gao
Huan Wang
Zhao Wang
Cong Zhang
Xiangjian Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1398913

4,526 views
7 citations

Review

Published on 10 Sep 2024

Role of stress and early-life stress in the pathogeny of inflammatory bowel disease

in Gut-Brain Axis

Bruno Bonaz
Valérie Sinniger
Sonia Pellissier

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1458918

6,552 views
16 citations

Clinical Trial

Published on 12 Jul 2024

Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke

in Gut-Brain Axis

Dazhi Deng
Hehua Lei
Zheng Cao
Cui Zhang
Ruichen Du
Xin Gao
Junjie Wei
Yibo Lu
Xiangzhen Zhou
Limin Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1378844

3,523 views
2 citations

Original Research

Published on 02 Jul 2024

Biopsy samples from patients with irritable bowel syndrome, but not from those with mastocytosis or unspecific gastrointestinal complaints reveal unique nerve activation in all gut regions independent of mast cell density, histamine content or specific gastrointestinal symptoms

in Gut-Brain Axis

Sheila Vignali
Sabine Buhner
Wolfgang Greiter
Hannelore Daniel
Thomas Frieling
Michael Schemann
Anita Annahazi

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1291554

2,987 views

Original Research

Published on 24 Jun 2024

Washed microbiota transplantation improves sleep quality in patients with sleep disorder by the gut-brain axis

in Gut-Brain Axis

Hongxin He
Manqing Li
Yifan Qiu
Zhiqing Wu
Lei Wu

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1415167

4,020 views
7 citations

Mini Review

Published on 03 Jun 2024

Molecular mechanisms and therapeutic possibilities of short-chain fatty acids in posttraumatic stress disorder patients: a mini-review

in Gut-Brain Axis

Pavlo Petakh
Khrystyna Duve
Valentyn Oksenych
Payam Behzadi
Oleksandr Kamyshnyi

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1394953

5,686 views
30 citations

Original Research

Published on 24 May 2024

Causal links between gut microbiomes, cytokines and risk of different subtypes of epilepsy: a Mendelian randomization study

in Gut-Brain Axis

Youjia Qiu
Bingyi Song
Minjia Xie
Yuchen Tao
Ziqian Yin
Menghan Wang
Chao Ma
Zhouqing Chen
Zhong Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1397430

4,196 views
5 citations

Original Research

Published on 22 May 2024

Deciphering the brain-gut axis: elucidating the link between cerebral cortex structures and functional gastrointestinal disorders via integrated Mendelian randomization

in Gut-Brain Axis

Zhiwei Xu
Fenglan Ning
Xuecheng Zhang
Qi Wang
Yimei Zhang
Yiting Guo
Hongling Jia

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1398412

4,872 views
1 citation

201 articles

articles

The brain-gut axis and chronic pain: mechanisms and therapeutic opportunities

Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression

Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice

Alzheimer's disease and gut-brain axis: Drosophila melanogaster as a model

Effects of repeated intragastric administrations with heat-inactivated Mycobacterium aurum DSM 33539 on the stress-induced aggravation of dextran sulfate sodium (DSS) colitis in C57BL/6N mice

Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial

Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome

Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research

Mechanisms of microbiota-gut-brain axis communication in anxiety disorders

Using lifestyle interventions and the gut microbiota to improve PTSD symptoms

Alterations of fractional anisotropy and white matter integrity in irritable bowel syndrome: a systematic review and meta-analysis of diffusion tensor imaging studies

Roles of the gut microbiota in human neurodevelopment and adult brain disorders

Aberrant intrinsic brain activities in functional gastrointestinal disorders revealed by seed-based d mapping with permutation of subject images

Cognotoxemia: endotoxemia and gender predict changes in working memory performance in healthy adults

Integrated gut microbiome and metabolomic analyses elucidate the therapeutic mechanisms of Suanzaoren decoction in insomnia and depression models

The role of the gut microbiota in neurodegenerative diseases targeting metabolism

Gut microbiota-derived acetate promotes long-term recovery through angiogenesis guided by lymphatic ingrowth in older adults with stroke

Role of stress and early-life stress in the pathogeny of inflammatory bowel disease

Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke

Biopsy samples from patients with irritable bowel syndrome, but not from those with mastocytosis or unspecific gastrointestinal complaints reveal unique nerve activation in all gut regions independent of mast cell density, histamine content or specific gastrointestinal symptoms

Washed microbiota transplantation improves sleep quality in patients with sleep disorder by the gut-brain axis

Molecular mechanisms and therapeutic possibilities of short-chain fatty acids in posttraumatic stress disorder patients: a mini-review

Causal links between gut microbiomes, cytokines and risk of different subtypes of epilepsy: a Mendelian randomization study

Deciphering the brain-gut axis: elucidating the link between cerebral cortex structures and functional gastrointestinal disorders via integrated Mendelian randomization