Frontiers in Neuroscience | Neurodevelopment

Original Research

Published on 06 Jun 2025

New variants and genotype-phenotype correlation of PPP3CA-related developmental and epileptic encephalopathy

in Neurodevelopment

Ting Wang
Shijia Ouyang
Xueyang Niu
Miaomiao Cheng
Ying Yang
Yonghua Yang
Quanzhen Tan
Wenwei Liu
Xiaoling Yang
Yuehua Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1570997

439 views

Review

Published on 06 Jun 2025

Mechanisms of brain overgrowth in autism spectrum disorder with macrocephaly

in Neurodevelopment

Laura Currey
Tracey Harvey
Alexandra Pelenyi
Michael Piper
Stefan Thor

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1586550

478 views

Original Research

Published on 03 Jun 2025

Association of genetic variants, protein domains, and phenotypes in the ZMIZ1 syndromic neurodevelopmental disorder

in Neurodevelopment

Kendall E. Cormier
Belle L. Kantor
Rajan K C
Xabier Blanco-Fernandez
Maria J. Galazo

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1605762

783 views

Brief Research Report

Published on 27 May 2025

Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia

in Neurodevelopment

Hannah Waxman
Marcus Kankkunen
Arya Gupta
Margo Dowgiewicz
Uwe Beffert
Angela Ho

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1589043

443 views

Original Research

Accepted on 23 May 2025

NEXMIF overexpression is associated with autism-like behaviors and alterations in dendritic arborization and spine formation in mice

in Neurodevelopment

KathrynAnn Odamah
Mauricio Toyoki Nishizawa Criales
Heng-Ye Man

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1556570

301 views

Original Research

Accepted on 23 May 2025

Development of Patient-Specific iPSC-Based Epilepsy Models and Identification of Differentially Expressed Genes for Disease Mechanisms

in Neurodevelopment

Jianfeng Wu
Siqi Huang
Lihao Chen
Yinghong Yang
Shunhan Zhang
Jiajia Xian
Xiaoyan Ma
Furong Ma
Li Shaoying
Yi Yang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1582255

178 views

Mini Review

Published on 21 May 2025

To recruit or to graft? Comparing the recruitment of resident non-neuronal cells by lineage reprogramming with engraftment of stem cell-derived neurons for neuronal replacement therapies

in Neurodevelopment

Daniel A. Peterson

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1589790

704 views

Original Research

Published on 19 May 2025

Axial and mean diffusivity predict myelin density in the hippocampus of pigs during early brain development, independent of sex

in Neurodevelopment

Loretta T. Sutkus
Zimu Li
Kaitlyn M. Sommer
Ryan N. Dilger

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1576274

907 views

Case Report

Published on 12 May 2025

Case Report: a novel homozygous ASNS variant in a Chinese female with severe microcephaly, encephalopathy and epilepsy

in Neurodevelopment

Shuangxi Cheng
Fang Zhang
Qingming Wang
Jianfei Zhang
Guizhen Lyu
Yanwei Li
Xinlong Zhou
Haiming Yuan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1570160

728 views

Perspective

Published on 07 May 2025

fNIRS as a biomarker for X-linked neurodevelopmental disorders: leveraging visual processing to assess brain function?

in Neurodevelopment

Elena Scaffei
Chiara Bosetti
Roberta Battini
Michela Fagiolini
Laura Baroncelli

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1560786

1,096 views

Original Research

Published on 30 Apr 2025

Laminar organization of the anterior olfactory nucleus—the interplay between neurogenesis timing and neuroblast migration

in Neurodevelopment

Eduardo Martin-Lopez
Bowen Brennan
Marion Lefèvre
Natalie J. Spence
Kimberly Han
Charles A. Greer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1546397

1,304 views

Original Research

Published on 29 Apr 2025

Heterozygous females from a rat model for creatine transporter deficiency reveal altered behavioral response to stressors, normal body weight and slight metabolic changes

in Neurodevelopment

Lara Duran-Trio
Marc Lanzillo
Dunja Simicic
Clothilde Roux-Petronelli
Stephen J. Bruce
Carmen Sandi
Cristina Cudalbu
Olivier Braissant

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1520550

1,099 views

Original Research

Published on 16 Apr 2025

Pregnant maternal brain dorsal anterior cingulate cortex choline/creatine ratios on 1H-MR spectroscopy in opioid exposure

in Neurodevelopment

Jonathan A. Class
Ramana V. Vishnubhotla
Yi Zhao
Nathan Ooms
David M. Haas
Senthilkumar Sadhasivam
Rupa Radhakrishnan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1569558

1,278 views

Original Research

Published on 03 Apr 2025

Comparative study of the effects of prenatal sevoflurane exposure at different cortical stages on forebrain development and maturation in offspring

in Neurodevelopment

Tianyuan Wang
Huandi Weng
Yalan Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1556703

1,007 views

Brief Research Report

Published on 26 Mar 2025

Clinical and molecular overlap between nucleotide excision repair (NER) disorders and DYRK1A haploinsufficiency syndrome

in Neurodevelopment

Nicolas Le May
Jérémie Courraud
Imène Boujelbène
Cathy Obringer
Tomoo Ogi
Alan R. Lehmann
Fanny Laffargue
Daphné Lehalle
Seiji Mizuno
Shehla Mohammed

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1554093

1,299 views

Original Research

Published on 20 Mar 2025

Characterizing stage-dependent neuromotor patterns in Drosophila melanogaster larvae through a graph construction approach

in Neurodevelopment

Yuri Bilk Matos
Nadezhda Velichkova
Mateo Kirchknopf Riera
Marcos Gomes Eleutério da Luz
Jimena Berni

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1557624

1,041 views