CASE REPORT article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1491918
Remarkable and sustained remission of an anaplastic thyroid carcinoma patient to the combined treatment of multimodal radiotherapy, anlotinib and toripalimab
Provisionally accepted
- West China Hospital, Sichuan University, Chengdu, China
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Anaplastic thyroid carcinoma (ATC) is an infrequent malignant tumor that has a high death rate and a poor prognosis. The therapeutic methods for ATC include traditional surgery, chemoradiotherapy and targeted therapy. However, the effect of ATC treatment is not ideal. We report a patient with ATC who developed rapid local recurrence and multiple systemic metastases after radical thyroidectomy. After multimodal radiotherapy, antiangiogenic therapy and immunotherapy, the patient's tumors shrunk significantly and achieved long-term control. The therapeutic effect was remarkable. These findings provide a viable new treatment choice for ATC patients in the future.
Keywords: Zhihui Li: Writing -review & editing. xin wu: Writing -review & editing. xuehu wu: Writing -original draft. Yurou Xing: Writingoriginal draft anaplastic thyroid carcinoma, Antiangiogenic drug, multimodal radiotherapy, Immunotherapy, Sustained remission anaplastic thyroid carcinoma
Received: 05 Sep 2024; Accepted: 30 Apr 2025.
Copyright: © 2025 Xing, wu, wu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: xin wu, West China Hospital, Sichuan University, Chengdu, China
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