Hepatic Epithelioid Hemangioendothelioma, a Rare Liver Tumor: A Case Report and Review of the Literature

Chao Deng¹Yulong An^1,2Jinli Liu^1,2Chao Wang³Haoxian Gou¹Jinpeng Zhang¹Minghui Gu¹Mengmeng Li⁴Tao Wang^1*Hao Luo^1,5*

• ¹Department of General Surgery, Western Theater General Hospital, Chengdu, Sichuan Province, China
• ²The Clinical Medical College of Southwest Medical University, Luzhou, Sichuan Province, China
• ³Department of Radiology, Western Theater General Hospital, Chengdu, Sichuan Province, China
• ⁴Western Theater General Hospital, Chengdu, Sichuan Province, China
• ⁵College of Medicine, Southwest Jiaotong University, Chengdu, Sichuan Province, China

asymptomatic. Subsequent positron emission tomography-computed tomography (PET-CT) examination suggested the possibility of benign lesions. Recent follow-up examinations revealed no further progression of the lesions; however, a biopsy of the lesions confirmed the diagnosis of HEHE. Comprehensive imaging studies, including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI), demonstrated scattered space-occupying lesions throughout the liver, with no evidence of distant metastasis. To minimize surgical trauma and preserve liver function, a multidisciplinary team was consulted, and a treatment plan was devised: liver resection in combination with microwave ablation of the lesions. The patient's postoperative recovery was uneventful, leading to successful hospital discharge.HEHE is characterized by its insidious onset and rarity, often presenting with multiple lesions at the time of clinical diagnosis. While liver transplantation may be considered the optimal treatment for multifocal HEHE, in cases where transplantation is not feasible, the combination of liver resection and microwave ablation of lesions may represent a safe and effective alternative therapeutic approach.