SYSTEMATIC REVIEW article

Front. Oncol.

Sec. Cancer Metabolism

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1532862

Scientometric analysis of lipid metabolism in macrophage polarization: 2013-2023

Provisionally accepted
Chenxiao  YeChenxiao Ye1Xiaosong  RuXiaosong Ru1Yong  GuoYong Guo2*
  • 1Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China
  • 2First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China

The final, formatted version of the article will be published soon.

Macrophage polarization plays a crucial role in the development of various diseases.Simultaneously, macrophage polarization is intimately related to lipid metabolism. To assess the emerging trend of lipid metabolism during macrophage polarization, the present study was carried out. CiteSpace was used to describe the emerging trends. 472 publications that explored lipid metabolism during macrophage polarization were gathered using the Web of Science Core Collection database (WoSCC). Between 2013 and 2023, 46 countries/regions involving 268 institutions carried out studies in this field. The largest number of publications was found in China. Additionally, the most recent burst keywords included "immunometabolism," "foam cell formation," and "pathway," which represented the current frontiers of research. In summary, the scientific output, teamwork, and research hotspots of lipid metabolism during macrophage polarization are thoroughly analyzed in this study.

Keywords: bibliometric analysis, Macrophage polarization, Lipid Metabolism, Tumor Microenvironment, Atherosclerosis

Received: 03 Feb 2025; Accepted: 30 May 2025.

Copyright: © 2025 Ye, Ru and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yong Guo, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China

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