CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1549825
Detection of gastric cancer with implantation metastasis to the inguinal region via 18F FAPI PET/CT: a case report
Provisionally accepted
- Northern Theater Command General Hospital, Shenyang, China
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Implantation metastasis of gastric cancer to the inguinal area is rarely reported, and a clear diagnosis of such metastasis is hard to make, especially when these cancers are invisible through fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET/CT) imaging. However, certain types of cancers, such as signet-ring cell carcinoma, are particularly sensitive to fibroblast activation protein inhibitor (FAPI) PET/CT. In this case, a patient who experienced gastric cancer and gastrectomy for two years, suddenly developed serious edema at his right lower limb. With the help of FAPI PET/CT and other laboratory findings, an abdominal implantation from his primary gastric cancer to the inguinal region was confirmed. After prompt treatment, the patient has got a favourable prognosis.
Keywords: gastric cancer, metastasis, PET/CT, FAPI, Radiotherapy
Received: 22 Dec 2024; Accepted: 18 Jun 2025.
Copyright: © 2025 Zhang, Hao, Wu, Wu, Liu, Xu, Zhang and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ying Yan, Northern Theater Command General Hospital, Shenyang, China
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