CASE REPORT article
Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1555098
Rare Diffuse Giant Cell Tumor of the Tendon Sheath in the Cervical Facet Joint
Provisionally accepted
- 1Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
- 2Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
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Giant Cell Tumor of the Tendon Sheath (GCTTS) is a rare neoplasm that can exhibit local aggressiveness but is generally benign. GCTTS is commonly classified into two subtypes: localized and diffuse, and rarely affects the axial skeleton. Diagnosing GCTTS in the spine is challenging, and it is associated with localized pain and neurological symptoms.Surgical resection is now the preferred treatment, though recurrence rates remain high. This report describes an exceptionally rare case of rapidly progressive and extensively invasive diffuse GCTTS affecting the lateral joints, surrounding vasculature, and nerves of the cervical spine. We also review the clinical presentation, imaging characteristics, and therapeutic outcomes of spinal GCTTS to enhance understanding and awareness of this rare pathology.
Keywords: Giant cell tumor of the tendon sheath, cervical spine, Vascular and Nerve compression, microneurosurgery, Recurrence
Received: 03 Jan 2025; Accepted: 09 Jun 2025.
Copyright: © 2025 Jiang, Xu, Ma and Luo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Junpeng Ma, Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
Tianyou Luo, Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
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