CASE REPORT article

Front. Oncol.

Sec. Surgical Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1557916

Giant Mesenteric Hemolymphangioma Enveloping the Ileum

Provisionally accepted
Guan-Ying  YuGuan-Ying YuQi  LiuQi LiuJing-Du  YanJing-Du YanXiao-Yan  ShiXiao-Yan ShiQing-Qing  YangQing-Qing YangBao-Xuan  WangBao-Xuan WangChengzhen  LiChengzhen LiPei-Ming  GuoPei-Ming GuoJie  JiaoJie JiaoHou-Jun  ZhangHou-Jun ZhangJing-Bo  ShiJing-Bo ShiLei  ZhangLei Zhang*
  • Jinan Central Hospital, Jinan, China

The final, formatted version of the article will be published soon.

Hemolymphangiomas are rare, benign tumors arising from lymphatic and vascular tissues, most commonly found in subcutaneous and soft tissues, with their occurrence in the gastrointestinal tract, especially the mesentery, being uncommon. Due to their heterogeneous imaging features, these tumors are often misdiagnosed as malignancies, particularly when located in the abdominal cavity. We report a case of a 16-year-old male presenting with abdominal pain, vomiting, and diarrhea for 7 days. Imaging revealed a large, heterogeneous mass in the right lower abdomen, initially suspected to be a malignant mesenteric tumor. An ultrasound-guided biopsy and immunohistochemistry confirmed the diagnosis of hemolymphangioma. The patient underwent a combined laparoscopic and open surgical approach, including en bloc resection of the tumor, along with a segment of the ileum and surrounding mesentery. Histopathological examination verified the presence of lymphatic and vascular components consistent with hemolymphangioma. The patient recovered uneventfully and showed no recurrence at a 3-month follow-up. Hemolymphangiomas, although rare, should be considered in the differential diagnosis of mesenteric tumors.

Keywords: Hemolymphangioma, abdominal mass, laparoscopic surgery, Gastrointestinal involvement, case report

Received: 09 Jan 2025; Accepted: 02 Jun 2025.

Copyright: © 2025 Yu, Liu, Yan, Shi, Yang, Wang, Li, Guo, Jiao, Zhang, Shi and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Lei Zhang, Jinan Central Hospital, Jinan, China

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