CASE REPORT article

Front. Oncol.

Sec. Surgical Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1558093

Coexistence of Castleman Disease and Gastric Stromal Tumor: A Case Report

Provisionally accepted
Jing  OuYangJing OuYangMuqing  LuoMuqing LuoMengtian  MaMengtian MaKun  ZhangKun Zhang*
  • The First Hospital of Hunan University of Chinese Medicine, Changsha, China

The final, formatted version of the article will be published soon.

Castleman's disease (CD) is a rare disorder that affects the lymph nodes and associated tissues. In contrast, gastrointestinal mesenchymal stromal tumor (GIST) is the most common mesenchymal tumor found in the gastrointestinal tract. The simultaneous occurrence of both conditions is exceedingly rare. We present a case of a patient whose imaging revealed a retroperitoneal pancreatic mass located below the neck and a small nodular protrusion on the lateral side of the greater curvature of the gastric body. This case was ultimately diagnosed as the coexistence of Castleman's disease and a gastric stromal tumor, as confirmed by MRI, CT, and postoperative histopathology. This report aims to enhance clinicians' understanding of this uncommon coexisting condition.

Keywords: Pathology, CT, MRI, Castleman disease (CD), Gastrointestinal Stromal Tumor

Received: 21 Feb 2025; Accepted: 28 Apr 2025.

Copyright: © 2025 OuYang, Luo, Ma and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Kun Zhang, The First Hospital of Hunan University of Chinese Medicine, Changsha, China

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