CASE REPORT article

Front. Oncol.

Sec. Head and Neck Cancer

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1564348

This article is part of the Research TopicMultidisciplinary Management of Oral Cancer: Diagnosis, Treatment, and RehabilitationView all 12 articles

Ultrasound-Guided Microwave Ablation Combined with Postoperative Radiotherapy and Chemotherapy for Advanced Tongue Cancer

Provisionally accepted
Ting  WeiTing WeiJiulong  DaiJiulong DaiTingting  LiTingting LiZiyue  HuZiyue HuLu  WangLu WangJuan  LiJuan LiJie  ZouJie ZouJia  FengJia FengMan  LuMan Lu*
  • Sichuan Cancer Hospital, Chengdu, China

The final, formatted version of the article will be published soon.

Background: While surgery remains the standard treatment for tongue cancer, it is associated with a range of functional and aesthetic sequelae. Additionally, ultrasound-guided microwave ablation (MWA) represents a promising minimally invasive alternative for patients with poor performance status or those unwilling to undergo surgery.Case Presentation: We report a 50-year-old male patient diagnosed with advanced tongue squamous cell carcinoma and cervical lymph node metastases. Microwave ablation was performed using a power setting of 30 W. Contrast-enhanced ultrasound conducted immediately afterward revealed no enhancement in the ablation area.Following the ablation, the patient received adjuvant radiotherapy and chemotherapy.During the procedure, the patient experienced minimal pain and no significant complications. After more than two years of follow-up, no evidence of metastasis or recurrence was observed, and the patient retained normal speech and swallowing functions.Conclusions: Ultrasound-guided MWA combined with radiotherapy and chemotherapy offers a safe, effective, and minimally invasive approach to the treatment of advanced tongue cancer.

Keywords: Ultrasonography, Microwave ablation, Tongue Neoplasms, Radiotherapy, Drug Therapy

Received: 21 Jan 2025; Accepted: 16 Jun 2025.

Copyright: © 2025 Wei, Dai, Li, Hu, Wang, Li, Zou, Feng and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Man Lu, Sichuan Cancer Hospital, Chengdu, China

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