CASE REPORT article

Front. Oncol.

Sec. Breast Cancer

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1571029

Case report: Primary leiomyosarcoma of the breast

Provisionally accepted
Haoqiang  LvHaoqiang Lv1Haiyang  RenHaiyang Ren2Shuang  ZhangShuang Zhang1Gen  DingGen Ding2Ping  TianPing Tian3*
  • 1Beidahuang Group Hongxinglong Hospital, Shuangyashan, China
  • 2Linyi Maternity and Child Health Care Hospital, Linyi, Shandong Province, China
  • 3Linyi People's Hospital, Linyi, China

The final, formatted version of the article will be published soon.

Primary leiomyosarcoma of the breast is an extremely rare tumor originating from the mesenchymal tissue of the breast. The clinical data of a case of primary leiomyosarcoma of the breast admitted to our hospital on September 11, 2024 were analyzed. A 58-year-old woman had a right breast mass for a week. Physical examination revealed an irregular mass at approximately 2-3 points in the right upper quadrant of the breast. Laboratory tests showed normal results for the tumor marker CA153.Color Doppler ultrasound considered solid nodules (BI-RADS Class 4b). Modified radical mastectomy and tertiary axillary lymph node dissection was performed on 2024-9-13, and the patient underwent adjuvant chemotherapy after surgery and recovered well. Pathological findings were reported one week after surgery: breast leiomyosarcoma.This article presents the diagnosis and treatment of primary leiomyosarcoma of breast through a clinical case, which provides a reference for clinicians. This case highlights the importance of pathological examination in the diagnosis of rare tumors, and suggests the need to combine imaging, laboratory examination and pathological findings to make a comprehensive judgment of breast masses.

Keywords: Breast1, Primary Leiomyosarcoma2, Sarcoma3, Breast malignancy4, Mastectomy5

Received: 04 Feb 2025; Accepted: 29 Apr 2025.

Copyright: © 2025 Lv, Ren, Zhang, Ding and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Ping Tian, Linyi People's Hospital, Linyi, China

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