CASE REPORT article

Front. Oncol.

Sec. Cardio-Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1575207

Primary cardiac angiosarcoma: a case report

Provisionally accepted
Yin  YuanYin Yuanzhao  yuzhao yuWenjie  DiaoWenjie Diaozelai  hezelai hejianming  dingjianming dingGengming  WangGengming Wang*
  • Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China

The final, formatted version of the article will be published soon.

Primary cardiac tumors are extremely rare, with an incidence rate ranging from only 0.17% to 0.33%. Clinically, their diagnosis is often delayed due to nonspecific clinical symptoms. This paper reports a case of primary cardiac angiosarcoma (PCAS) pathologically confirmed via surgery, presenting with recurrent palpitations during exertion as the initial symptom. The patient subsequently developed bilateral lung and liver metastases and received chemotherapy. Through a comprehensive review of the literature, this report explores the diagnostic and therapeutic strategies for PCAS, with a focus on analyzing the mechanisms underlying the atypical disease course, the rationale for treatment decisions, and the key clinical insights.

Keywords: Primary cardiac angiosarcoma, Surgery, cardiac tumor, chemotherapy, Multidisciplinary team

Received: 12 Feb 2025; Accepted: 02 May 2025.

Copyright: © 2025 Yuan, yu, Diao, he, ding and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Gengming Wang, Department of Radiotherapy, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China

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