CASE REPORT article
Front. Oncol.
Sec. Gynecological Oncology
Hemorrhagic Giant Intra-Abdominal Desmoid Tumor in Twin Pregnancy: A Case Report and Literature Review
Provisionally accepted
- Second Hospital of Hebei Medical University, Shijiazhuang, China
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Background: Desmoid tumors (DTs) are rare, non-metastatic fibroblastic neoplasms known for their local invasiveness and slow growth. Their occurrence during pregnancy is rare, presenting unique diagnostic and therapeutic challenges, especially when complications like hemorrhage develop. Spontaneous hemorrhage in intra-abdominal DTs is an exceptionally rare complication. Case Presentation: We report a 31-year-old woman, 32+4 weeks into a twin pregnancy, with a history of successful IVF-ET and routine prenatal care, who presented with acute left abdominal pain and signs of hemorrhagic shock. A computed tomography (CT) scan revealed a giant intra-abdominal mass (23.6×15.6×17.3 cm) with active bleeding. An emergency cesarean section and tumor resection were performed, which revealed a desmoid tumor (DT) invading the pancreas and transverse colon. Postoperative recovery was uneventful, and the patient was discharged in stable condition. Conclusion: This case underscores the importance of early multidisciplinary intervention in managing rare pregnancy-associated desmoid tumors (DT) complicated by hemorrhage. It emphasizes the necessity of heightened clinical suspicion in pregnant women presenting with acute abdominal pain.
Keywords: Desmoid tumor, Soft tissue tumors, Pregnancy, Intra-abdominal, Hemorrhage
Received: 12 Feb 2025; Accepted: 07 Nov 2025.
Copyright: © 2025 Wang, Du, Huang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zeqing Du, 28804421@hebmu.edu.cn
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