ORIGINAL RESEARCH article
Front. Oncol.
Sec. Pediatric Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1577066
This article is part of the Research TopicInnovations in Supportive Care in Global Pediatric OncologyView all 4 articles
Building and sustaining infection prevention and control teams at two pediatric cancer units in Ecuador and Guatemala through a collaboration partnership
Provisionally accepted
- 1Department of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, United States
- 2St. Jude Children's Research Hospital, Memphis, Tennessee, United States
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Background: Hospital infection prevention and control (IPC) programs are often insufficient to meet the needs of pediatric oncology units (POUs) in low-resource settings. Accordingly, we established partnerships to build and sustain dedicated IPC teams for two POUs in Ecuador and Guatemala. Methods: Each partnership comprised four phases: (1) planning and preparation; (2) developing the IPC team; (3) sustaining the IPC team; and (4) integrating the IPC team into the institution. The impact of the IPC teams was assessed by monitoring healthcare-associated infections (HAIs) and compliance with IPC practices. Results: At Hospital SOLCA–Quito, Ecuador, local champions were identified and trained. These in turn built local IPC teams that led healthcare improvement by using surveillance for outcome measures, monitoring practices for processes measures, and staff training. As the collaboration progressed, infection rates decreased steadily. At SOLCA–Quito, there were 9 HAIs/1000 patient days at baseline in 2010, whereas at the end of 2019, there were 2.6 HAIs/1000 patient days. A similar program was developed at the UNOP hospital in Guatemala, where the HAI rate decreased from 9.9/1000 patient days in 2011 to 5.37/1000 patient days in 2019 and the CLABSI rate decreased from 32.75/1000 catheter days in 2008 to 3.11/1000 catheter days in 2019. Towards the end of the collaborations, the IPC teams were integrated into the institutional structures. The Ecuadorean IPC team was integrated as a link team between the pediatric oncology service and the hospital IPC program. The Guatemalan team became the institutional IPC program staff. Conclusions: Our collaborations decreased HAIs in two POUs. The model proved sustainable and became part of the institutional structures, and it has been replicated in POUs elsewhere.
Keywords: Pediatric1, Cancer2, low- and middle-income countries3, infection prevention andcontro4, link teams5, Ecuador6, Guatemala7
Received: 14 Feb 2025; Accepted: 25 Aug 2025.
Copyright: © 2025 Caniza. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Miguela A. Caniza, Department of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, United States
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