CASE REPORT article
Front. Oncol.
Sec. Pediatric Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1578541
This article is part of the Research TopicAdvancements and Challenges in Retroperitoneal Approaches for Urological SurgeriesView all 4 articles
Adrenal angiomatoid fibrous histiocytoma misdiagnosed as pheochromocytoma: a case report
Provisionally accepted
- The Second Affiliated Hospital of GuangXi Medical University, Nanning, Guangxi Zhuang Region, China
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Background: Adrenal angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that is frequently misdiagnosed preoperatively. This report describes a case of adrenal AFH that was successfully managed via retroperitoneal laparoscopic adrenalectomy. Case introduction: An 18-year-old male presented with a two-week history of recurrent abdominal pain and vomiting. Preoperative computed tomography angiography and urography suggested a pheochromocytoma. Pheochromocytoma was initially suspected based on preoperative computed tomography angiography and urography findings; however, postoperative pathological analysis confirmed the diagnosis as adrenal angiomatoid fibrous histiocytoma. There was no recurrence of adrenal angiomatoid fibrous histiocytoma during the follow-up of 10 months. Conclusions: Adrenal AFH is a rare tumor with a high propensity for misdiagnosis. It should be considered in the differential diagnosis of adrenal masses with imaging features suggestive of hemangioma. Surgical resection is the primary treatment, and the prognosis is generally favorable without the need for adjuvant radiotherapy or chemotherapy.
Keywords: Adrenal angiomatoid fibrous histiocytoma, case reports, soft tissue, surgical resection, Laparoscopic adrenalectomy
Received: 03 Jun 2025; Accepted: 15 Sep 2025.
Copyright: © 2025 Yao, Peng, Bi, Chen, Wang, Zhang and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Haipeng Huang, haipeng377@163.com
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