ORIGINAL RESEARCH article
Front. Oncol.
Sec. Skin Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1580453
This article is part of the Research TopicPromising Photosensitive Agents for Photodynamic TherapyView all 16 articles
Trends and Emerging Frontiers of Photodynamic Therapy for Non-Melanoma Skin Cancer (1979–October 2024): A Bibliometric Analysis
Provisionally accepted- Department of Dermatology, The General Hospital of Air Force, Beijing, China
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Introduction: Photodynamic therapy (PDT) is a non-invasive treatment modality for non-melanoma skin cancer (NMSC). This study aims to use bibliometric analysis to explore the research trends and development in the field of PDT for NMSC, identifying key hotspots and emerging directions.Methods: This study conducted a comprehensive literature search in the Web of Science Core Collection database and applied bibliometric analysis and visualization using tools such as VOSviewer, CiteSpace, and the R package “bibliometrix”.Results: A total of 358 publications were analyzed, with the USA led in contributions and collaborations, with Yale University being the top institution. The Journal of the American Academy of Dermatology made contributions to the field. Prominent authors included Richard L. Edelson, Arthur H. Rook, and Robert S. Stern. The keywords were categorized into four distinct clusters. The keywords were concentrated into four clusters: Treatment methods and targeted conditions, Cellular and immune responses, Clinical applications and therapeutic management and Techniques and research methodologies. Keywords such as “versus host disease” and “extracorporeal photopheresis” continue to emerge prominently in 2024.Conclusion: This study provides a comprehensive overview of the distribution patterns and key research hotspots in the field of PDT for NMSC. Future research trends should focus on treatment technologies and immune responses.
Keywords: non-melanoma skin cancer, Photodynamic therapy, bibliometric analysis, VOSviewer, Citespace
Received: 20 Feb 2025; Accepted: 19 Jun 2025.
Copyright: © 2025 CHEN, Bai, Lu, Chen, Wang, Sun, Li and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: QI CHEN, Department of Dermatology, The General Hospital of Air Force, Beijing, China
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