CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1583882
Successful endoscopic full-thickness resection(EFTR) of an irregular submucosal tumor of the esophagus with surface focal white patches：horseshoe-shaped leiomyoma
Provisionally accepted
- Jining First People's Hospital, Jining, China
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Esophageal leiomyoma is a rare benign tumor of the esophagus, accounting for approximately 1.2% of all esophageal tumors. Endoscopically, it typically appears as a protrusion into the esophageal lumen with intact and smooth mucosa, which can be slightly moved with biopsy forceps and rarely causes luminal stenosis. The current case presents an irregular submucosal esophageal mass with localized white patches on the surface-an endoscopic appearance not previously reported. These surface white patches complicated the diagnosis, and the postoperative pathological finding of a horseshoe-shaped leiomyoma is even more unusual. Preoperative imaging with chest and abdominal CT and endoscopic ultrasound identified the lesion in the muscularis propria, and successful endoscopic full-thickness resection was performed. This minimally invasive approach was confirmed by pathology to be precise, safe, and effective, achieving treatment outcomes comparable to traditional surgical resection.
Keywords: Endoscopic full-thickness resection, Irregular submucosal tumor of the esophagus, White patches, Horseshoe-shaped leiomyoma, endoscopic ultrasound
Received: 26 Feb 2025; Accepted: 16 Jul 2025.
Copyright: © 2025 Pan, Wang, Zhang, Fan and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Li -juan Fan, Jining First People's Hospital, Jining, China
Ran Ma, Jining First People's Hospital, Jining, China
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