SYSTEMATIC REVIEW article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1585383
This article is part of the Research TopicAI-Powered Insights: Predicting Treatment Response and Prognosis in Breast CancerView all 9 articles
Effect of Mindfulness-based stress on cancer-related fatigue in breast cancer patients:A systematic review and meta-analysis
Provisionally accepted
- School of Nursing, Dalian Medical University, Dalian, China
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Abstract Background: Cancer-related fatigue (CRF) can seriously affect the quality of life of breast cancer patients. Mindfulness-based stress reduction therapy (MBSR) has been increasingly used in the treatment of breast cancer patients to reduce psychological distress and promote emotional and physical health. This review aims to provide an updated assessment of the role of MBSR in reducing CRF and sleep quality in breast cancer patients. Objective: To evaluate the effect of MBSR on cancer-related fatigue in patients with breast cancer. Methods: Computer search PubMed, Embase, Web of Science, Wanfang and other databases, We were able to search for articles related to CRF from MBSR in breast cancer patients from the establishment of the database to October 2023. Researchers independently screened the literature and extracted information. The meta-analysis was performed using Review Manager Software (version 5.3). Results: A meta-analysis of 7 studies included showed that MBSR could reduce CRF in breast cancer patients (SMD = -0.86, 95%CI = −1.22 ~ −0.50). Improved sleep quality (MD = -2.54, 95%CI = −3.38 ~ −1.70). Conclusion: Our study suggests that MBSR may be associated with reductions in cancer-related fatigue and improvements in quality of life among patients with breast cancer; however, these findings should be interpreted with caution due to the moderate quality of evidence and substantial heterogeneity observed across included studies.
Keywords: MBSR, breast cancer, Cancer-related fatigue, Meta-analysis, Patient
Received: 20 Mar 2025; Accepted: 09 Sep 2025.
Copyright: © 2025 Gao, Pang and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lei Gao, School of Nursing, Dalian Medical University, Dalian, China
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