ORIGINAL RESEARCH article
Front. Oncol.
Sec. Gastrointestinal Cancers: Colorectal Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1587422
This article is part of the Research TopicNational Colorectal Cancer Awareness Month 2025: Current Progress and Future Prospects on Colorectal Cancer Prevention, Diagnosis and TreatmentView all 8 articles
Decoding Colorectal Cancer Lung Metastasis: A Global Research Odyssey
Provisionally accepted
- 1Jiangnan University, Wuxi, China
- 2Nantong University, Nantong, Jiangsu Province, China
- 3Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China
- 4Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: Colorectal cancer (CRC) remains a major global health burden, particularly when complicated by pulmonary metastasis (PM), which significantly worsens prognosis and reduces survival despite active treatment. The absence of standardized therapeutic strategies for CRC with PM has driven research into its underlying biological mechanisms, including epithelialmesenchymal transition, immune evasion, and tumor microenvironment dynamics. Methods: A bibliometric analysis was conducted on 2,645 publications related to CRC with PM retrieved from the Web of Science Core Collection (1991Collection ( -2025)). Analytical tools such as CiteSpace and VOSviewer were employed to map the intellectual structure, collaboration networks, and
Keywords: bibliometric analysis, colorectal cancer, Pulmonary metastases, Molecular mechanisms, Surgical treatment As research on
Received: 04 Mar 2025; Accepted: 07 Jul 2025.
Copyright: © 2025 Zhang, Wang, Fu, Duan, Wang, Chen and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaoyu Liu, Nantong University, Nantong, 226019, Jiangsu Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.