CASE REPORT article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1589001
Great Saphenous Vein Leiomyosarcoma: A rare case report and literature review
Provisionally accepted
- 1Zhejiang Provincial People's Hospital, Hangzhou, China
- 2Hangzhou Third People's hospital, Hangzhou, Jiangsu Province, China
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Great Saphenous Vein Leiomyosarcoma is an extremely rare tumor clinically which is ofen misdiagnosed as vein thrombosis due to atypical clinical manifestations. This report describes a rare presentation of Great Saphenous Vein Leiomyosarcoma in a 37-year-old male who was referred to our hospital due to an incremental painless mass on his left shank. Ultrasound revealed the mass in the left calf is a solid tumor originated from the left great saphenous vein. He underwent radical resection for the mass ultimately. Subsequent histopathological and immunohistochemical analyses made a conclusive diagnosis of primary Leiomyosarcoma originated from Great Saphenous Vein. There are only 56 cases of Great Saphenous Vein Leiomyosarcoma reported in medical databases worldwide at present which are summarized and analyzed here.
Keywords: Leiomyosarcoma, Great saphenous vein, ultrasound, Hypoecho, case report
Received: 06 Mar 2025; Accepted: 06 Jun 2025.
Copyright: © 2025 Liu, Dong, Hou, Litao, He, Ling and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qiaohong Hu, Zhejiang Provincial People's Hospital, Hangzhou, China
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