CASE REPORT article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1590725
Dual Malignancies: A Case Report of Sequential Occurrence of Trichilemmal Tumour and 1 Breast Carcinoma in a 56-year-old female
Provisionally accepted
- 1Department of Medical Oncology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research, Chennai, India
- 2Department of Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, India
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The authors present a rare case of the sequential occurrence of a malignant trichilemmal tumour 15 (MPTT) and invasive ductal carcinoma of the breast in a 56-year-old female. The patient initially 16 presented with a palpable breast lump and a longstanding asymptomatic scalp swelling since 17 childhood. Histopathological evaluation confirmed the breast lump as invasive ductal carcinoma, 18 while the scalp swelling, initially suspected to be a benign cyst, was diagnosed as an MPTT. The 19 patient underwent combination chemotherapy, which resulted in a favourable response of the breast 20 carcinoma; however, the MPTT exhibited a discordant therapeutic outcome. Trichilemmal carcinoma 21 is an uncommon cutaneous neoplasm, and its coexistence with breast carcinoma represents an 22 exceedingly rare clinical scenario. Furthermore, the differential response of these malignancies to 23 chemotherapy presents a significant therapeutic challenge. This case underscores the importance of 24 accurate diagnosis, individualised treatment strategies, and a multidisciplinary approach for optimally 25 managing such complex oncological presentations.
Keywords: trichilemmal tumour, breast carcinoma, chemotherapy, Ductal carcinoma, Myocardial Infarction
Received: 12 Mar 2025; Accepted: 20 Oct 2025.
Copyright: © 2025 Vuppumalla, A, M, Javvaji and Vagha. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ravichandran A, raviambalathandi@gmail.com
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