CORRECTION article

Front. Oncol., 29 May 2025

Sec. Pharmacology of Anti-Cancer Drugs

Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1590809

This article is part of the Research TopicNew Technologies in Cancer Diagnostics and TherapeuticsView all 44 articles

Corrigendum: LCT-3d induces oxidative stress-mediated apoptosis by upregulating death receptor 5 in gastric cancer cells

Menglin Wang&#x;Menglin Wang1†Xinxin Wu&#x;Xinxin Wu1†Lu Yu&#x;Lu Yu1†Zi-yun HuZi-yun Hu1Xiaobo LiXiaobo Li1Xia MengXia Meng1Chun-tao LvChun-tao Lv1Gi-Young KimGi-Young Kim2Yung Hyun ChoiYung Hyun Choi3Zhenya Wang*Zhenya Wang1*Hai-Wei Xu*Hai-Wei Xu1*Cheng-Yun Jin,*Cheng-Yun Jin1,4*
  • 1Key Laboratory of Advanced Technology for Drug Preparation, Ministry of Education, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China
  • 2Department of Marine Life Sciences, Jeju National University, Jeju, Republic of Korea
  • 3Department of Biochemistry, College of Oriental Medicine, Dong-Eui University, Busan, Republic of Korea
  • 4State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, China

A Corrigendum on
LCT-3d induces oxidative stress-mediated apoptosis by upregulating death receptor 5 in gastric cancer cells

by Wang M, Wu X, Yu L, Hu Z-y, Li X, Meng X, Lv C-t, Kim G-Y, Choi YH, Wang Z, Xu H-W and Jin C-Y (2021). Front. Oncol. 11:658608. doi: 10.3389/fonc.2021.658608

In the published article, an author name was incorrectly written as “Zhengya Wang”. The correct spelling is “Zhenya Wang”.

In the published article, there was an error in Figure 2 as published. During the post-submission stage, while organizing and editing the figures, we failed to conduct a thorough check, resulting in a fundamental error in Figure 2 of the manuscript: the duplication of Western Blot bands (strip 2 of MGC803 cells and strip 4 of HGC-27 cells in Figure 2. The corrected Figure 2 and its caption LCT-3d triggered Caspase mediated apoptotic pathway in gastric cancer cells appear below.

Figure 2
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Figure 2. LCT-3d triggered Caspase mediated apoptotic pathway in gastric cancer cells. (A) MGC803 cells and HGC27 were cells treated with various concentrations of LCT-3d for 48 h and apoptosis analyzed by flow cytometry. (B) Cells were treated as in (A) and the expression of Cleaved-Caspase and Cleaved PARP was analyzed by Western blotting. (C) MGC803 cells and HGC27 cells were pretreated with a pan-Caspase inhibitor, Z-VAD-FMK (100 µM) for 1 h, followed by incubation with LCT-3d (4 µM) for 48 h. Flow cytometric analysis on the effect of Z-VAD-FMK on LCT-3d-induced cells apoptosis.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: LCT-3d, DR5, reactive oxygen species, Nrf2, apoptosis, gastric cancer

Citation: Wang M, Wu X, Yu L, Hu Z-y, Li X, Meng X, Lv C-t, Kim G-Y, Choi YH, Wang Z, Xu H-W and Jin C-Y (2025) Corrigendum: LCT-3d induces oxidative stress-mediated apoptosis by upregulating death receptor 5 in gastric cancer cells. Front. Oncol. 15:1590809. doi: 10.3389/fonc.2025.1590809

Received: 10 March 2025; Accepted: 16 May 2025;
Published: 29 May 2025.

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Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2025 Wang, Wu, Yu, Hu, Li, Meng, Lv, Kim, Choi, Wang, Xu and Jin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Cheng-Yun Jin, Y3lqaW5Aenp1LmVkdS5jbg==; Hai-Wei Xu, WGh3ZWkwMUAxMjYuY29t; Zhenya Wang, emhlbnlhd2FuZ0B6enUuZWR1LmNu

These authors have contributed equally to this work and share first authorship

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.