ORIGINAL RESEARCH article
Front. Oncol.
Sec. Genitourinary Oncology
This article is part of the Research TopicApproaches and Advances in Urologic Cancer EpidemiologyView all 3 articles
Prediction of early urinary continence after radical prostatectomy based on preoperative pelvic floor parameters: A retrospective study
Provisionally accepted
- First Hospital, Peking University, Beijing, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Background: Postoperative urinary incontinence is one of the most significant complications following radical prostate cancer surgery. We aimed to predict the risk of urinary incontinence within one month of radical prostatectomy (RP) using preoperative physiological parameters of the pelvic floor muscles. Methods: This is a retrospective study with a convenience sample. A cohort of 188 patients with prostate cancer was recruited from March to December 2023 from a single urology department at Peking University First Hospital. The cohort was divided into a training set of 132 patients and a validation set of 56 patients at a 7:3 ratio. This study used multivariate logistic regression analysis to predict urinary incontinence and calculated the area under the receiver operating characteristic curve (AUC) for model validation. Nomograms and calibration plots were generated for training sets. Preoperative and operative parameters were collected, including age, body mass index (BMI), International Prostate Symptom Score (IPSS), prostate-specific antigen (PSA) level, Gleason score, surgical method, urethral reconstruction, lymph node dissection, nerve-sparing status, catheterization duration, D'Amico risk classification, American Society of Anesthesiologists (ASA) score, Charlson Comorbidity Index, postoperative duration, prostate volume, and pelvic floor muscle parameters. Results: The incidence of urinary incontinence within a month after RP was 78.7%. Advanced age and low fast-twitch muscle scores have emerged as independent risk factors for urinary incontinence. Patients older than 70 had a 6.283-fold higher risk of incontinence compared to those younger than 60 (95% CI: 1.47-26.95). The fast-twitch muscle score was significantly associated with the risk of incontinence (OR=1.25; 95% CI: 1.05-1.49). The AUC was 0.764 (95% CI: 0.675-0.854) for the training set and 0.776 (95% CI: 0.644-0.908) for the validation set, with calibration plots indicating high model accuracy. Conclusions: Advanced age and low fast-twitch muscle scores in functional level were significant risk factors for RP. This risk predictive model enables healthcare professionals to perform accurate preoperative risk assessments and predictions based on patients' individualized indicators, and provide tailored postoperative rehabilitation strategies.
Keywords: Urinary Incontinence, prostate cancer, Radical Prostatectomy, pelvic floor muscle parameters, prediction
Received: 11 Mar 2025; Accepted: 25 Nov 2025.
Copyright: © 2025 Yu, Han, Huang, Liu, Chen, Zhang, Meng and Che. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shuhui Yu
Yisen Meng
Xinyan Che
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.