REVIEW article
Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1594232
Sleep Disturbances in Brain Tumors: A Narrative Review
Provisionally accepted
- 1Department of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, China
- 2The Second Medical College of Lanzhou University, Lanzhou, China
- 3The First School of Clinical Medicine, Lanzhou University, Lanzhou, China
- 4Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Individuals with brain tumors are more susceptible to comorbid sleep disturbances, which significantly impair daytime functioning, quality of life, and long-term prognosis. A bidirectional relationship between sleep and brain tumors has been suggested, with sleep disturbances in this population being diverse and multifactorial, stemming from neurotransmitter imbalances, treatment interventions, and comorbidities conditions throughout the disease course. While sleep assessment and intervention guidelines exist for cancer more broadly, specific recommendations for neuro-oncological etiology populations remain limited. As awareness grows regarding the negative impact of poor sleep in patients with brain tumors, there is an urgent need for more targeted research to systematically characterize sleep disturbances and explore therapeutic implications. In this context, we conducted a narrative review current on sleep research in patients with brain tumors.
Keywords: brain tumor, Sleep disturbances, insomnia, Narcolepsy, prognosis
Received: 15 Mar 2025; Accepted: 15 Aug 2025.
Copyright: © 2025 Liang, Hu, Yang, Pan, Zhang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qiang Li, Department of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, China
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