CASE REPORT article
Front. Oncol.
Sec. Cardio-Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1596237
This article is part of the Research TopicCardiomyopathy and Heart Failure in OncologyView all 3 articles
MRI features of primary cardiac lymphoma： case report and literature review
Provisionally accepted
- People’s Hospital of Deyang City, Deyang, China
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Purpose: To further enhance the understanding of the imaging features of primary cardiac lymphoma (PCL), improve preoperative diagnostic accuracy, and reduce the misdiagnosis rate.Methods: This study reports a case of a 63 -year -old male who presented with three -daylong dizziness and bilateral lower limb edema. Initial transthoracic echocardiography detected a 4.5×5 cm mass without blood flow in the right atrium, suspecting it as a thrombus or tumor. Subsequently, cardiac MRI (Philips 3.0T Ingenia) was performed. Pre -contrast black blood turbo spin echo(TSE) T1WI, T2WI, fat saturation T2 (STIR), and retrospective ECG -triggered balanced turbo field echo (steady state free precession) sequences on short and long axes were used.Results: MRI showed a roundish solid mass in the right atrium with clear margins, broadbased attachment to the anterior/posterior walls, adjacent right atrial wall thickening, inferior vena cava inlet narrowing, and protrusion into the tricuspid orifice during atrial systole. First -pass perfusion presented homogeneous progressive enhancement, while the delayed phase showed patchy irregular enhancement. Due to limited knowledge of PCL, a preliminary diagnosis of cardiac myxoma was made. Eventually, tumor resection was carried out, and postoperative pathology confirmed it as Right Atrial Diffuse Large B -Cell Lymphoma (DLBCL) with a Ki -67 proliferation index of 90%. Although symptoms improved post -surgery, the patient refused further chemotherapy and died soon.Conclusion: This case highlights that MRI plays a significant role in the diagnosis of PCL, helping to identify characteristic imaging features and reduce misdiagnosis. Preoperative biopsy is crucial for accurate diagnosis, and chemotherapy is essential for improving patient survival. Further research is needed to better understand the imaging features of this rare tumor and optimize treatment strategies.
Keywords: primary cardiac lymphoma, MRI, Right atrial, Tomor, literature review
Received: 19 Mar 2025; Accepted: 13 Jun 2025.
Copyright: © 2025 xie, zou, tang and li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: qing zou, People’s Hospital of Deyang City, Deyang, China
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