ORIGINAL RESEARCH article
Front. Oncol.
Sec. Thoracic Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1597585
This article is part of the Research TopicExploring the Tumor Microenvironment in Resectable Lung CancerView all 3 articles
Lung Cancer-Associated Fibroblasts-Mediated Collagen Deposition Drives Mediastinal Lymph Node Metastasis in Non-Small Cell Lung Cancer
Provisionally accepted
- 1Department of Cardiothoracic Surgery, Wuhan Pu'ai Hospital, Wuhan, China
- 2The University of Hong Kong, Pokfulam, Hong Kong, SAR China
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Kong with his thesis entitled "Nonsmall cell lung cancer: from bench to bedside". He is a Specialist in Respiratory Medicine in Hong Kong, Fellow of the American College of Chest Physicians, Fellow of the Royal College of Physicians and Surgeons of Glasgow, Fellow of the Royal College of Physicians of Edinburgh and London. He underwent basic research in lung cancer biology at the Cleveland Clinic Foundation, USA from 2000-01. Among his various appointments in professional societies, he was the President of the Hong Kong Thoracic Society in 2011-13, Chairman of the Hong Kong Lung Foundation (2021-23) and Chairman of the Specialty Board in Respiratory Medicine of the Hong Kong College of Physicians (2021-23). In 2024, he served as an Executive Committee member of the Asian Pacific Society of Respirology (APSR) and the Co-President of APSR 2024 Congress held in Hong Kong.Prof. Ho has an established track record in lung cancer research, and the areas of focus over the years include preclinical models, the role of antioxidants, epidemiology, diagnostics, and clinical trials. He has been frequently involved as a principal investigator in multicenter international clinical trials on novel lung cancer therapeutics. He has published more than 170 papers in peer-reviewed journals
Keywords: cancer-associated fibroblasts, Lymphangiogenesis, Mediastinal lymph node metastasis, NSCLC, Orthotopic xenograft model
Received: 21 Mar 2025; Accepted: 30 May 2025.
Copyright: © 2025 Chen, Ho, Feng, Ko, Lam and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: James CM Ho, The University of Hong Kong, Pokfulam, 999077, Hong Kong, SAR China
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