ORIGINAL RESEARCH article

Front. Oncol.

Sec. Cancer Metabolism

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1598911

Brian [18F]FDG PET Associations of Cervical Cancer-Related Peripheral Inflammatory markers

Provisionally accepted
  • 1Department of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China
  • 2School of Psychology, Nanjing Normal University, Nanjing, Jiangsu Province, China
  • 3Jiangsu Key Laboratory of Mental Health and Cognitive Science, School of Psychology, Nanjing Normal University, Nanjing, Liaoning Province, China
  • 4NHC Key Laboratory of Nuclear Medicine and Jiangsu Key Laboratory of Molecular Nuclear Medicine, Wuxi, China

The final, formatted version of the article will be published soon.

The purpose of this study was to explore brain metabolic correlates of peripheral inflammatory markers in patients with cervical cancer (CC).: Cervical cancer (CC) patients (267) without treatments who underwent [18F] Fluorodeoxyglucose ([18F]FDG) positron-emission tomography (PET) / computed tomography (CT) were retrospectively studied. All CC patients were grouped into the International Federation of Gynecology and Obstetrics (FIGO) stage II (n=16), the FIGO stage III (n=160), and the FIGO stage IV (n=91) according to the FIGO stage. According to the median of metabolic tumor volume (MTV) or total lesion glycolysis (TLG) for primary tumor in different FIGO stage, CC patients in different FIGO stage were grouped into the Low_MTV (TLG) group (

Keywords: regional brain glucose metabolism, cervical cancer, Peripheral inflammatory markers, tumor metabolic parameters, PET

Received: 24 Mar 2025; Accepted: 09 Jun 2025.

Copyright: © 2025 Hu, Zhong and Hu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yuxiao Hu, Department of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China

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