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CASE REPORT article

Front. Oncol.

Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1599953

Undifferentiated embryonic sarcoma of the adult liver: a case report

Provisionally accepted
Shengyong  LiShengyong Li*Lexin  BaoLexin BaoXiujun  LiXiujun LiLiang  BaiLiang Bai
  • Weihai Municipal Hospital, Weihai, China

The final, formatted version of the article will be published soon.

Undifferentiated embryonal sarcoma of the liver is a malignant mesenchymal tumor of the liver that predominantly affects children, with exceedingly rare occurrence in adults, and is associated with a poor prognosis. We present a case of Undifferentiated embryonal sarcoma of the liver in a previously healthy 45-year-old male, admitted to our hospital due to fever.Magnetic resonance imaging revealed a cystic-solid mass in the right lobe of the liver, measuring approximately 15*13*13cm in size. Imaging diagnosis raised suspicion of biliary cystadenocarcinoma with hemorrhage. A hepatic resection was successfully performed for the patient, and the histologic diagnosis was Undifferentiated embryonal sarcoma of the liver. The patient received a chemotherapy regimen of ifosfamide combined with epirubicin after surgery, and no recurrence was observed after 6 months of follow-up. We herein review the clinical, radiologic and pathologic features of this rare tumor.

Keywords: Undifferentiated embryonal sarcoma, Liver, Long-term survival, Multidisciplinary treatment, Adult

Received: 25 Mar 2025; Accepted: 26 Jun 2025.

Copyright: © 2025 Li, Bao, Li and Bai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Shengyong Li, Weihai Municipal Hospital, Weihai, China

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