REVIEW article
Front. Oncol.
Sec. Cancer Molecular Targets and Therapeutics
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1602489
Approaches to Modeling Cancer Metastasis: From Bench to Bedside
Provisionally accepted
- 1Binzhou Medical University, Binzhou, China
- 2Medical Research Center, Binzhou Medical University Hospital, Binzhou, Shandong Province, China
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Cancer metastasis modeling requires multidisciplinary approaches that integrate experimental, computational, and clinical research to unravel the complexities of cancer spread (1). By deepening our understanding of the metastatic process, researchers can efficiently and precisely develop targeted therapies and personalized treatment strategies to relieve the burden of metastasis on patients. In this review, we highlight the critical roles of experimental models in advancing knowledge of metastasis, identifying therapeutic targets, evaluating treatment strategies, and improving patient outcomes. These models serve as essential tools for translational research and drug discovery in the fight against metastatic cancer.
Keywords: Ha, S.-E., Wu, M., Zogg, H., Ronkon, C. F., Lee, M.-Y., van Beek, M. E. A., Schurink, I. J., Rosmark, O.
Received: 29 Mar 2025; Accepted: 22 Jul 2025.
Copyright: © 2025 Sun, Zhou, Yin, Wang and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Fei Wang, Medical Research Center, Binzhou Medical University Hospital, Binzhou, 256603, Shandong Province, China
Lijuan Yang, Medical Research Center, Binzhou Medical University Hospital, Binzhou, 256603, Shandong Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.