ORIGINAL RESEARCH article
Front. Oncol.
Sec. Cancer Metabolism
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1603148
This article is part of the Research TopicEndothelium, Innate Immunity and Coagulation in Hematological DisordersView all 17 articles
Thromboelastography for the Evaluation of Coagulation Function in Patients with Hepatic Echinococcosis During the Perioperative Period: A Retrospective Study
Provisionally accepted
- Qinghai Provincial People's Hospital, Xining, China
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Objective: To study the application of thrombolysis diagram (TEG) and routine coagulation test in the evaluation of coagulation function in patients with hepatic hydatid.The observation group consisted of 69 cases of hydatid liver patients undergoing elective combined segmenectomy, and the control group consisted of 69 healthy subjects. The correlation analysis of TEG, six coagulation items and PLT in the preoperative observation group and control group was conducted. The differences of TEG, hemagglutination six and PLT between the two groups were compared. TEG and coagulation function indexes of observation group were compared at different time during perioperative period.In the control group, The time of blood cell aggregation (K) was negatively correlated with prothrombin time (PT), fibrinogen (FIB) and platelet count (PLT) ; The maximum strength of blood clot (MA) was positively correlated with PT, FIB and PLT; The rate of blood cell aggregation (Angle) is positively correlated with PT, FIB and PLT; the comprehensive index of blood coagulation (CI) was positively correlated with FIB and PLT. The reaction time of blood coagulation (R) of observation group was positively correlated with PT; MA was positively correlated with PT, FIB and PLT; MA was negatively correlated with thrombin time (TT). activated partial thromboplastin time (APTT), D-dimer (DD),, PLT, R value, K value, Angle, MA and CI were compared between the two groups, and the differences were statistically significant (P<0.05). Compared with T1, APTT, R value, Angle and MA in observation group were significantly decreased at T2 and T3 (P<0.05); Compared with T1, PT, TT, FIB and K values had no significant changes (P>0.05).The coagulation function of liver hydatid patients was relatively low during the perioperative period, TEG is more sensitive to changes in perioperative coagulation function and can comprehensively understand the patient's coagulation state.
Keywords: Coagulation abnormalities, Hepatic echinococcosis, Hypohepatia, Platelet aggregation function, thromboelastography (TEG)
Received: 31 Mar 2025; Accepted: 31 Jul 2025.
Copyright: © 2025 Zheng, Wang, Yuan, Wang, He and A. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xing Zheng, Qinghai Provincial People's Hospital, Xining, China
Zongzhao He, Qinghai Provincial People's Hospital, Xining, China
Jide A, Qinghai Provincial People's Hospital, Xining, China
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