CASE REPORT article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1604170
Case Report: Late Simultaneous Metastasis of Renal Clear Cell Carcinoma to the Ampulla and Breast
Provisionally accepted
- 1Fourth People’s Hospital of Jinan, Jinan, China
- 2Shandong Public Health Clinical Center, Jinan, Shandong Province, China
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We present the case of a 67-year-old female who developed simultaneous metastases to the ampulla of Vater and the breast. Her medical history is significant for a radical nephrectomy performed twenty-one years prior for renal cell carcinoma (RCC). The patient was referred for evaluation due to the development of progressive jaundice, fatigue, and weight loss. A computed tomography (CT) scan of the abdomen revealed a 40 mm nodule located at the ampulla of Vater, accompanied by dilatation of the bile duct, indicative of obstructive jaundice. Additionally, ultrasonography identified a mass approximately 20 mm in size in the lateral portion of the left breast. The patient underwent a pancreatoduodenectomy to address the ampullary mass and a lumpectomy for the breast lesion. Histological examination of the resected specimens confirmed the diagnosis of metastases from RCC in both the ampulla of Vater and the breast.
Keywords: Renal cell carcinoma, Ampullary mass, obstructive jaundice, metastatic breast cancer, Cancer
Received: 01 Apr 2025; Accepted: 31 Jul 2025.
Copyright: © 2025 Dai, Li, Sun and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Gangpu Wang, Fourth People’s Hospital of Jinan, Jinan, China
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