CASE REPORT article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1606872
Case Report of misdiagnosis: A Rare Case of Hepatic Epithelioid Hemangioendothelioma Characterized Primarily by Fever
Provisionally accepted
- 1Yunnan University, Kunming, China
- 2The First People’s Hospital of Yunnan Province, Kunming, Yunnan Province, China
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This study reports a case of a 47-year-old female who was initially misdiagnosed as having liver abscess due to repeated fever, and was later misdiagnosed again as liver inflammatory myofibroblastic tumor(IMT) after liver biopsy. After surgical removal, molecular pathological examination confirmed the diagnosis of Hepatic epithelioid hemangioendothelioma(HEHE). HEHE with fever as the main symptom is extremely rare and there are no similar reports available at present. This study summarizes the key points of HEHE diagnosis and treatment, analyzes the reasons for the misdiagnosis in this case and the possible factors causing the fever symptoms, highlights the difficulties in HEHE diagnosis and the significant value of molecular pathology in its diagnosis.
Keywords: Hepatic epithelioid hemangioendothelioma, liver inflammatory myofibroblastic tumor, Misdiagnosis, case report, Fever
Received: 06 Apr 2025; Accepted: 15 Aug 2025.
Copyright: © 2025 Zhao and Dang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yanli Dang, The First People’s Hospital of Yunnan Province, Kunming, Yunnan Province, China
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