ORIGINAL RESEARCH article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1611729
The Impact of Intraoperative Neuromonitoring Combined with Evidence-based Nursing on Vocal Cord Function, Emotional State, Pain, and Quality of Life in Patients After Total Thyroidectomy for Thyroid Cancer: A Comprehensive Study
Provisionally accepted
Dandan Chen
Kun Shang*- Henan Provincial People's Hospital, Zhengzhou, China
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Objective To evaluate the impact of intraoperative neuromonitoring (IONM) combined with evidence-based nursing on vocal function, emotional status, pain levels, and quality of life (QoL) in patients undergoing total thyroidectomy for thyroid cancer.Methods A single-center randomized controlled trial was conducted. The intervention group received IONM with evidence-based nursing, while the control group underwent IONM with conventional nursing. Outcomes were assessed using the Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS) for pain, EORTC QLQ-C30 for 1-month postoperative QoL, and Voice Handicap Index simplified Chinese version (VHI-10) combined with laryngoscopy for vocal recovery and complications.Compared to controls, the intervention group exhibited significantly lower postoperative VHI-10 scores (5 (2, 8) vs 7 (4, 11), P<0.001), reduced HADS anxiety scores (5 (2, 8) vs 10 (4, 12), P<0.001), and lower 24-hour NRS pain scores (3 (1, 4) vs 4 (2.75, 4.25), P<0.001). The intervention group also demonstrated marked improvements in QLQ-C30 global health status (83 (73.75, 86) vs 77 (72.75, 80), P=0.001), shorter operative duration (92.467±16.916 vs 107.93±24.26 min, P<0.001), reduced intraoperative blood loss (16.5 (9.75, 24) vs 23.5 (11.75, 32) mL, P=0.005), and lower postoperative drainage (59 (30, 77.25) vs 82 (46.5, 110.25) mL, P=0.001).The integration of IONM with evidence-based nursing significantly enhanced postoperative recovery and QoL in thyroid cancer patients. Future studies should prioritize larger cohorts, long-term follow-up, and comparisons across surgical techniques to strengthen clinical recommendations. This multimodal approach demonstrates significant potential for optimizing patient-centered outcomes in thyroid surgery.
Keywords: Thyroidectomy, intraoperative neuromonitoring, Evidence-Based Nursing, Vocal cord recovery, thyroid cancer
Received: 14 Apr 2025; Accepted: 24 Jun 2025.
Copyright: © 2025 Chen and Shang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Kun Shang, Henan Provincial People's Hospital, Zhengzhou, China
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