CASE REPORT article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1614376
Thyroid Metastases from Breast Cancer: A Case Report and Brief Literature Review
Provisionally accepted
- 1Department of breast and thyroid, Peking University Shenzhen Hospital, Shenzhen, China
- 2Shenzhen university medical school, Shenzhen, China
- 3PKU-Shenzhen Clinical Institute of Shantou University Medical College, Shantou, Guangdong Province, China
- 4Depaertment of Oncology, Peking University Shenzhen Hospital, Shenzhen, China
- 5Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China
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Thyroid metastasis from breast cancer is a rare occurrence and often indicates a poor prognosis. We report the case of a young female patient with thyroid metastasis from breast cancer after being diagnosed with the Graves' diseaseprimary hyperthyroidism, and review the clinical characteristics and diagnostic approach of thyroid metastases. The mechanism may be associated with altered microenvironment induced by the Graves' diseasehyperthyroidism and Hashimoto's thyroiditis. Thyroid function and abnormal imaging examination should be paid attention during breast cancer patients' follow-up. Early identification and individualized treatment of thyroid metastasis may contribute to prolonged survival and improved quality of life.
Keywords: thyroid metastases, breast cancer, Immunohistochemistry, diagnosis, Treatment
Received: 18 Apr 2025; Accepted: 29 Aug 2025.
Copyright: © 2025 He, Li, Wang, Nong, Li, Yin and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaoling Liu, Department of breast and thyroid, Peking University Shenzhen Hospital, Shenzhen, China
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