CASE REPORT article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1616331
This article is part of the Research TopicImaging in the Diagnosis and Treatment of Eye DiseasesView all 31 articles
Retinal Metastasis from lung adenocarcinoma: a case report
Provisionally accepted
- Second Affiliated Hospital of Jilin University, Changchun, China
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Retinal metastasis is an exceedingly rare manifestation of systemic cancer, accounting for less than 1% of ocular metastases. Lung adenocarcinoma is among the primary tumors that can metastasize to the retina, though such cases are seldom reported.We present a 70-year-old male with a history of lung adenocarcinoma who presented with a decline in vision in his left eye. Fundus examination revealed a large yellowwhite lesion with hemorrhage in the macula and temporal retina. Multimodal imaging, including optical coherence tomography (OCT) and fluorescein angiography (FA), confirmed the diagnosis of retinal metastasis. This case underscores the importance of considering retinal metastasis in cancer patients with visual disturbances. Early diagnosis through comprehensive ophthalmic evaluation is crucial to avoid misdiagnosis
Keywords: Retinal metastasis, Lung Adenocarcinoma, Ocular metastasis, Multimodal Imaging, case report, Optical Coherence Tomography
Received: 22 Apr 2025; Accepted: 22 Jul 2025.
Copyright: © 2025 Li, Luo, Yang and Xiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jun Xiao, Second Affiliated Hospital of Jilin University, Changchun, China
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